Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | PPOX | P50336 | 4/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11410920 | 0.81 | GAA (0.47) | GAATSHRPPARDSMN1; SMN2GLA | |
| SCHEMBL2523355 | 0.81 | GAA (0.45) | GAATSHRPPARDSMN1; SMN2GLA | |
| SCHEMBL2523426 | 0.80 | NPC1 (0.52) | GAATSHRPPARDSMN1; SMN2GLA | |
| SCHEMBL16341129 | 0.80 | GAA (0.48) | GAATSHRPPARDSMN1; SMN2GLA | |
| SCHEMBL13922744 | 0.80 | CSNK2A1 (0.47) | GAATSHRSMN1; SMN2GLAADRA2A | |
| Alclofenac SCHEMBL10600369 | 0.78 | PPARD (0.62) | GAATSHRPPARDSMN1; SMN2NPC1 | |
| Alclofenac SCHEMBL25703 | 0.78 | PPARD (0.62) | GAATSHRPPARDSMN1; SMN2NPC1 | |
| SCHEMBL11013101 | 0.78 | GAA (0.50) | GAATSHRPPARDSMN1; SMN2ADRA2A | |
| Alclofenac SCHEMBL29350515 | 0.78 | PPARD (0.62) | GAATSHRPPARDSMN1; SMN2NPC1 | |
| SCHEMBL10977759 | 0.77 | CSNK2A1 (0.65) | TSHRSMN1; SMN2GLACSNK2A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009124371-A9 | NOVEL COMPOUNDS DERIVED FROM TAURINE, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE | EMS S. A. (BR) | 2010-12-02 | — | — | WO | claimed |
| WO-2009124371-A2 | NOVEL COMPOUNDS DERIVED FROM TAURINE, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE | EMS S. A. (BR) | 2009-10-15 | — | — | WO | claimed |
| US-4505898-A | ANTIINFLAMMATORY AGENTS; OLIGOPEPTIDES | BERK PHARMACEUTICAS LTD. (GB) | 1985-03-19 | — | — | US | claimed |
| US-4452783-A | ANTIINFLAMMATORY AGENTS, POLYPEPTIDES | BERK PHARMACEUTICAS LTD. (GB) | 1984-06-05 | — | — | US | claimed |
| US-4014997-A | ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1977-03-29 | — | — | US | claimed |
| US-3988446-A | Glycerides with anti-inflammatory properties | ABBOTT LABORATORIES (US) | 1976-10-26 | — | — | US | claimed |
| US-4546106-A | ANTIARTHRITIC AGENTS | MERCK & CO., INC. (US) | 1985-10-08 | — | — | US | disclosed |
| US-4505898-A | ANTIINFLAMMATORY AGENTS; OLIGOPEPTIDES | BERK PHARMACEUTICAS LTD. (GB) | 1985-03-19 | — | — | US | disclosed |
| US-4452783-A | ANTIINFLAMMATORY AGENTS, POLYPEPTIDES | BERK PHARMACEUTICAS LTD. (GB) | 1984-06-05 | — | — | US | disclosed |
| US-4452783-A | ANTIINFLAMMATORY AGENTS, POLYPEPTIDES | BERK PHARMACEUTICAS LTD. (GB) | 1984-06-05 | — | — | US | disclosed |
| US-4355034-A | Ethenyl derivatives of mercaptoalkylpyridines as anti-inflammatory agents | MERCK & CO., INC. (US) | 1982-10-19 | — | — | US | disclosed |
| US-4217352-A | ANTIARTHRITIC AGENT | MERCK & CO., INC. (US) | 1980-08-12 | — | — | US | disclosed |
| US-4212976-A | ANTIARTHRITIC AGENTS | MERCK & CO., INC. (US) | 1980-07-15 | — | — | US | disclosed |
| US-4144342-A | ANTIARTHRITIC AND ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. (US) | 1979-03-13 | — | — | US | disclosed |
| US-4061759-A | ANTIINFLAMMATORY, ARTHRITIS | MERCK & CO., INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4057637-A | RHEUMATOID ARTHRITIS | MERCK & CO., INC. (US) | 1977-11-08 | — | — | US | disclosed |
| US-3971797-A | ANTIARTHRITIC | MERCK & CO., INC. (US) | 1976-07-27 | — | — | US | disclosed |