Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3454598 | 0.90 | SCD (0.56) | SCDPPARAMAPT | |
| SCHEMBL3454999 | 0.82 | SCD (0.59) | SCDPPARA | |
| SCHEMBL3455532 | 0.81 | SCD (0.60) | SCD | |
| SCHEMBL3455386 | 0.80 | SCD (0.56) | SCDNPC1ALDH1A1SMN1; SMN2PPARA | |
| SCHEMBL3454995 | 0.80 | SCD (0.58) | SCDNPC1HPGD | |
| SCHEMBL12464376 | 0.79 | SCD (0.60) | SCDNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL3454983 | 0.79 | SCD (0.48) | SCDNPC1PPARAHPGD | |
| SCHEMBL3454096 | 0.75 | SMN1; SMN2 (0.51) | NPC1ALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL3454417 | 0.74 | SCD (0.59) | SCDNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL3455543 | 0.74 | SCD (0.51) | SCDNPC1PPARAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007143597-A9 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2010-11-11 | — | — | WO | claimed |