Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3454216 | 0.84 | CDC7 (0.54) | KDM4ERAB9AGAANPC1KMT2A | |
| SCHEMBL3454854 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2KDM4ERAB9AGAANPC1 | |
| SCHEMBL3455546 | 0.82 | SMN1; SMN2 (0.60) | SMN1; SMN2KDM4ERAB9AGAANPC1 | |
| SCHEMBL3454995 | 0.81 | SCD (0.58) | NPC1HPGD | |
| SCHEMBL3454983 | 0.78 | SCD (0.48) | NPC1HPGD | |
| SCHEMBL3454195 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2KDM4ERAB9AGAANPC1 | |
| SCHEMBL3455386 | 0.77 | SCD (0.56) | SMN1; SMN2GAANPC1ALDH1A1HPGD | |
| SCHEMBL3454598 | 0.77 | SCD (0.56) | MAPT | |
| SCHEMBL3454331 | 0.76 | SMN1; SMN2 (0.41) | SMN1; SMN2KDM4ERAB9AGAANPC1 | |
| SCHEMBL3455448 | 0.75 | SCD (0.58) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007143597-A9 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2010-11-11 | — | — | WO | claimed |
| WO-2007143597-A9 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2010-11-11 | — | — | WO | disclosed |