SCHEMBL3456466

SCHEMBL3456466

O=C(O)C(CS)NS

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3456469 1.00
SCHEMBL2588998 1.00
Methane SCHEMBL28262578 0.97
Butane SCHEMBL9042138 0.91 KDM4E (0.54)
Propene SCHEMBL9979271 0.87 KDM4E (0.50)
SCHEMBL23552453 0.80 KDM4E (0.54)
SCHEMBL313275 0.80 KDM4E (0.54)
SCHEMBL29596626 0.80 KDM4E (0.58)
SCHEMBL4263217 0.79
SCHEMBL18703772 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040241706-A1 Highly specific modulators of GTPases for target validation IRM, LLC 2004-12-02 US claimed
WO-2004024082-A2 HIGHLY SPECIFIC MODULATORS OF GTPASES FOR TARGET VALIDATION IRM, LLC (GB) 2004-03-25 WO claimed
US-20250320250-A1 PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VISCERAL PAIN IRONWOOD PHARMACEUTICALS INC (US) 2025-10-16 US disclosed
US-12194065-B2 Methods and compositions to enhance metabolic detoxification systems NATURE'S SUNSHINE PRODUCTS, INC. (US) 2025-01-14 US disclosed
US-20240392280-A1 PRODUCTS AND METHODS FOR ASSESSING AND INCREASING KLOTHO PROTEIN LEVELS KLOTHO THERAPEUTICS, INC. 2024-11-28 US disclosed
EP-4440595-A1 PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VISCERAL PAIN Ironwood Pharmaceuticals, Inc. (US) 2024-10-09 EP disclosed
US-12030923-B2 Compositions and methods for producing a composition BRISTOL-MYERS SQUIBB COMPANY (US) 2024-07-09 US disclosed
CN-117750978-A Synthetic peptide shuttle bioconjugates for intracellular cargo delivery 费尔丹生物公司 2024-03-22 CN disclosed
CN-219861313-U Production equipment of yeast extract rich in glutathione 康艾维食品科技(上海)有限公司 2023-10-20 CN disclosed
US-20230202967-A1 COMPOSITIONS AND METHODS FOR TREATING ATHEROSCLEROTIC CARDIOVASCULAR DISEASE GAVISH-GALILEE BIO APPLICATIONS LTD. (IL) 2023-06-29 US disclosed
WO-2023097309-A1 PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VISCERAL PAIN IRONWOOD PHARMACEUTICALS, INC. (US) 2023-06-01 WO disclosed
EP-1024838-A1 STABLE RADIOIODINE CONJUGATES AND METHODS FOR THEIR SYNTHESIS Immunomedics, Inc. (US) 2000-08-09 EP disclosed
WO-1999026591-A2 IMPROVED HAIR PERMING AGENT SDG, INC. (US) 1999-06-03 WO disclosed
WO-1999011294-A1 STABLE RADIOIODINE CONJUGATES AND METHODS FOR THEIR SYNTHESIS IMMUNOMEDICS, INC. (US) 1999-03-11 WO disclosed
EP-0789551-A4 HAIR CARE PERMING AGENTS AND PROCESSES LAU JOHN R (US) 1998-12-02 EP disclosed
US-5690956-A Hair care perming agent SDG, INC. (US) 1997-11-25 US disclosed
EP-0789551-A1 HAIR CARE PERMING AGENTS AND PROCESSES LAU, John R. (US) 1997-08-20 EP disclosed
WO-1997011672-A1 HAIR CARE PERMING AGENTS AND PROCESSES LAU JOHN R (US) 1997-04-03 WO disclosed
US-5370991-A Forms complex with elastase and inhibits elastinolytic activity of elastase THE CENTER FOR BLOOD RESEARCH, INC. (US) 1994-12-06 US disclosed
EP-0065867-A1 Optical resolution of DL-cysteine Nohira, Hiroyuki (JP) 1982-12-01 EP disclosed