SCHEMBL3456469

SCHEMBL3456469

O=C(O)[C@H](CS)NS

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3456466 1.00
SCHEMBL2588998 1.00
Methane SCHEMBL28262578 0.97
Butane SCHEMBL9042138 0.91 KDM4E (0.54)
Propene SCHEMBL9979271 0.87 KDM4E (0.50)
SCHEMBL23552453 0.80 KDM4E (0.54)
SCHEMBL313275 0.80 KDM4E (0.54)
SCHEMBL29596626 0.80 KDM4E (0.58)
SCHEMBL4263217 0.79
SCHEMBL18703772 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040241706-A1 Highly specific modulators of GTPases for target validation IRM, LLC 2004-12-02 US claimed
WO-2004024082-A2 HIGHLY SPECIFIC MODULATORS OF GTPASES FOR TARGET VALIDATION IRM, LLC (GB) 2004-03-25 WO claimed
US-12630830-B2 Gene editing tools Life Technologies Corporation (US) 2026-05-19 US disclosed
CN-121319227-B Caffeic acid-amino acid composite grafted starch and preparation method and application thereof 合肥工业大学 2026-05-15 CN disclosed
EP-4401757-B1 GENE EDITING TOOLS LIFE TECHNOLOGIES CORP (US) 2026-03-25 EP disclosed
WO-2025235681-A1 HALOGENATED METAL CHELATORS AND USES THEREOF CORNELL UNIVERSITY (US) 2025-11-13 WO disclosed
US-12453762-B2 Complex comprising a cell penetrating peptide, a cargo and a TLR peptide agonist for treatment of glioblastoma AMAL THERAPEUTICS SA (CH) 2025-10-28 US disclosed
EP-4634116-A1 VANADIUM COMPLEXES WITH NITROGEN AND OXYGEN DONOR ATOMS Borchers GmbH (DE) 2025-10-22 EP disclosed
US-20250320250-A1 PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VISCERAL PAIN IRONWOOD PHARMACEUTICALS INC (US) 2025-10-16 US disclosed
US-12403181-B2 Combination of interleukin-2 with an interleukin 1 inhibitor, conjugates and therapeutic uses thereof ILTOO PHARMA (FR) 2025-09-02 US disclosed
EP-3634530-B1 METHODS AND SYSTEMS FOR REMOVING CARBON DIOXIDE ADVITOS GMBH (DE) 2025-07-02 EP disclosed
EP-1024838-A1 STABLE RADIOIODINE CONJUGATES AND METHODS FOR THEIR SYNTHESIS Immunomedics, Inc. (US) 2000-08-09 EP disclosed
WO-1999026591-A2 IMPROVED HAIR PERMING AGENT SDG, INC. (US) 1999-06-03 WO disclosed
WO-1999011294-A1 STABLE RADIOIODINE CONJUGATES AND METHODS FOR THEIR SYNTHESIS IMMUNOMEDICS, INC. (US) 1999-03-11 WO disclosed
EP-0789551-A4 HAIR CARE PERMING AGENTS AND PROCESSES LAU JOHN R (US) 1998-12-02 EP disclosed
US-5690956-A Hair care perming agent SDG, INC. (US) 1997-11-25 US disclosed
EP-0789551-A1 HAIR CARE PERMING AGENTS AND PROCESSES LAU, John R. (US) 1997-08-20 EP disclosed
WO-1997011672-A1 HAIR CARE PERMING AGENTS AND PROCESSES LAU JOHN R (US) 1997-04-03 WO disclosed
US-5370991-A Forms complex with elastase and inhibits elastinolytic activity of elastase THE CENTER FOR BLOOD RESEARCH, INC. (US) 1994-12-06 US disclosed
EP-0065867-A1 Optical resolution of DL-cysteine Nohira, Hiroyuki (JP) 1982-12-01 EP disclosed