Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4557257 | 1.00 | PKM (0.39) | PKMSLC1A2SLC1A1CHRNB2CHRNA4 | |
| SCHEMBL3456930 | 1.00 | PKM (0.39) | PKMSLC1A2SLC1A1CHRNB2CHRNA4 | |
| SCHEMBL2173721 | 1.00 | PKM (0.39) | PKMSLC1A2SLC1A1CHRNB2CHRNA4 | |
| SCHEMBL4557253 | 1.00 | PKM (0.39) | PKMSLC1A2SLC1A1CHRNB2CHRNA4 | |
| SCHEMBL2175939 | 1.00 | PKM (0.39) | PKMSLC1A2SLC1A1CHRNB2CHRNA4 | |
| SCHEMBL4557254 | 1.00 | PKM (0.39) | PKMSLC1A2SLC1A1CHRNB2CHRNA4 | |
| SCHEMBL1366378 | 0.82 | PKM (0.36) | PKMSLC1A2SLC1A1CHRM2CHRM3 | |
| SCHEMBL27672142 | 0.81 | PKM (0.38) | PKMSLC1A2SLC1A1CHRNB2CHRNA4 | |
| SCHEMBL2176665 | 0.81 | PKM (0.38) | PKMSLC1A2SLC1A1CHRNB2CHRNA4 | |
| SCHEMBL2176249 | 0.81 | PKM (0.38) | PKMSLC1A2SLC1A1CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2264030-A1 | Substituted cyclic hydroxamates as inhibitors of matrix metalloproteinases | Incyte Corporation (US) | 2010-12-22 | — | — | EP | disclosed |