Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2772509 | 1.00 | AGTR1 (1.00) | AGTR1 | |
| SCHEMBL2772907 | 0.91 | AGTR1 (0.88) | AGTR1 | |
| SCHEMBL2774276 | 0.90 | AGTR1 (1.00) | AGTR1 | |
| SCHEMBL2778212 | 0.88 | AGTR1 (0.86) | AGTR1 | |
| SCHEMBL2773271 | 0.88 | AGTR1 (0.85) | AGTR1 | |
| SCHEMBL13475109 | 0.85 | AGTR1 (0.85) | AGTR1 | |
| SCHEMBL2777965 | 0.85 | AGTR1 (1.00) | AGTR1 | |
| SCHEMBL2775199 | 0.84 | AGTR1 (0.85) | AGTR1 | |
| SCHEMBL2774172 | 0.83 | AGTR1 (0.83) | AGTR1 | |
| SCHEMBL2775131 | 0.83 | AGTR1 (0.94) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2253630-A1 | Heterocyclic compound and use thereof | Takeda Pharmaceutical Company Limited (JP) | 2010-11-24 | — | — | EP | disclosed |