Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13017251 | 1.00 | HTR2A (0.33) | HTR2ASLC6A4KCNH2CRHR1RXRA | |
| SCHEMBL3457149 | 0.77 | MAPK1 (0.45) | HTR2ASLC6A4KCNH2CRHR1RXRA | |
| SCHEMBL28099918 | 0.74 | AR (0.40) | HTR2ASLC6A4KCNH2 | |
| SCHEMBL1278451 | 0.73 | HTR2A (0.40) | HTR2ASLC6A4KCNH2 | |
| SCHEMBL119682 | 0.73 | HTR2A (0.40) | HTR2ASLC6A4KCNH2 | |
| SCHEMBL4428667 | 0.73 | HTR2A (0.40) | HTR2ASLC6A4KCNH2 | |
| SCHEMBL29427853 | 0.73 | HTR2A (0.40) | HTR2ASLC6A4KCNH2 | |
| SCHEMBL912518 | 0.69 | HTR2A (0.37) | HTR2ASLC6A4KCNH2 | |
| SCHEMBL912517 | 0.69 | HTR2A (0.37) | HTR2ASLC6A4KCNH2 | |
| SCHEMBL374922 | 0.69 | HTR2A (0.37) | HTR2ASLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2264010-A1 | Hetarylamidines | Bayer CropScience AG (DE) | 2010-12-22 | — | — | EP | disclosed |