Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MPL | P40238 | 3/20 | 0.38 |
| ▸ | CDK8 | P49336 | 2/20 | 0.36 |
| ▸ | FLT1 | P17948 | 2/20 | 0.35 |
| ▸ | FLT4 | P35916 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13017251 | 0.77 | HTR2A (0.33) | HTR2ASLC6A4KCNH2CRHR1RXRA | |
| SCHEMBL3457258 | 0.77 | HTR2A (0.33) | HTR2ASLC6A4KCNH2CRHR1RXRA | |
| SCHEMBL7896608 | 0.74 | MEN1 (0.46) | HTR2ASLC6A4KCNH2MPLCDK8 | |
| SCHEMBL249549 | 0.70 | MPL (0.42) | HTR2ASLC6A4KCNH2MPLCDK8 | |
| SCHEMBL248689 | 0.70 | TRPA1 (0.45) | HTR2ASLC6A4KCNH2MPLCDK8 | |
| SCHEMBL3929860 | 0.68 | CDK8 (0.41) | HTR2ASLC6A4KCNH2CDK8FLT1 | |
| SCHEMBL24385774 | 0.67 | HTR2A (0.46) | HTR2ASLC6A4KCNH2ARPLA2G7 | |
| SCHEMBL1283223 | 0.67 | ALDH1A1 (0.50) | MAPK1HTR2ASLC6A4KCNH2MPL | |
| SCHEMBL1973743 | 0.67 | MAPT (0.49) | MAPK1MPLCDK8NPSR1AR | |
| SCHEMBL2323118 | 0.67 | ADORA2A (0.67) | MPLNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2264010-A1 | Hetarylamidines | Bayer CropScience AG (DE) | 2010-12-22 | — | — | EP | disclosed |
| EP-2264010-A1 | Hetarylamidines | Bayer CropScience AG (DE) | 2010-12-22 | — | — | EP | disclosed |