Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.61 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.61 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | CPA1 | P15085 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7667976 | 1.00 | CA5A (0.61) | CA5ACA5BFFAR3LCKFYN | |
| Acetic Acid SCHEMBL28587428 | 1.00 | CA5A (0.61) | CA5ACA5BFFAR3LCKFYN | |
| Acetic Acid SCHEMBL78900 | 1.00 | — | — | |
| Acetic Acid SCHEMBL8350356 | 1.00 | CA5A (0.61) | CA5ACA5BFFAR3LCKFYN | |
| Acetic Acid SCHEMBL11518561 | 0.96 | CA5A (0.57) | CA5ACA5BFFAR3LCKFYN | |
| Acetic Acid SCHEMBL9342214 | 0.96 | CA5A (0.57) | CA5ACA5BFFAR3LCKFYN | |
| Acetic Acid SCHEMBL17312003 | 0.96 | CA5A (0.57) | CA5ACA5BFFAR3LCKFYN | |
| Acetic Acid SCHEMBL10884476 | 0.96 | CA5A (0.57) | CA5ACA5BFFAR3LCKFYN | |
| Acetic Acid SCHEMBL7224260 | 0.96 | — | — | |
| Acetic Acid SCHEMBL10481221 | 0.96 | CA5A (0.57) | CA5ACA5BFFAR3LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7674427-B2 | Rare earth metal member and making method | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-03-09 | — | — | US | claimed |
| CN-100587116-C | Rare earth metal member and making method | SHINETSU CHEMICAL CO | 2010-02-03 | — | — | CN | claimed |
| EP-1739196-B1 | Rare earth metal member of high surface purity and making method | SHINETSU CHEMICAL CO (JP) | 2009-02-18 | — | — | EP | claimed |
| CN-1891393-A | Preflux composition | BAIK YANG CHEMICAL CO LTD (KR) | 2007-01-10 | — | — | CN | claimed |
| CN-1891863-A | Rare earth metal member and making method | SHINETSU CHEMICAL CO (JP) | 2007-01-10 | — | — | CN | claimed |
| US-20070003790-A1 | Rare earth metal member and making method | SHIN-ETSU CHEMICAL CO., LTD. | 2007-01-04 | — | — | US | claimed |
| EP-1739196-A1 | Rare earth metal member of high surface purity and making method | Shin-Etsu Chemical Co., Ltd. (JP) | 2007-01-03 | — | — | EP | claimed |
| CN-116194420-A | Building compositions | 建筑研究和技术有限公司 | 2023-05-30 | — | — | CN | disclosed |
| US-7674427-B2 | Rare earth metal member and making method | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-03-09 | — | — | US | disclosed |
| CN-100587116-C | Rare earth metal member and making method | SHINETSU CHEMICAL CO | 2010-02-03 | — | — | CN | disclosed |
| EP-1739196-B1 | Rare earth metal member of high surface purity and making method | SHINETSU CHEMICAL CO (JP) | 2009-02-18 | — | — | EP | disclosed |
| US-7471924-B2 | Cleaning unit and image forming apparatus | FUJI XEROX CO., LTD. (JP) | 2008-12-30 | — | — | US | disclosed |
| US-20070020005-A1 | Cleaning unit and image forming apparatus | FUJI XEROX CO., LTD. (JP) | 2007-01-25 | — | — | US | disclosed |
| CN-1891393-A | Preflux composition | BAIK YANG CHEMICAL CO LTD (KR) | 2007-01-10 | — | — | CN | disclosed |
| CN-1891863-A | Rare earth metal member and making method | SHINETSU CHEMICAL CO (JP) | 2007-01-10 | — | — | CN | disclosed |
| US-20070003790-A1 | Rare earth metal member and making method | SHIN-ETSU CHEMICAL CO., LTD. | 2007-01-04 | — | — | US | disclosed |
| EP-1739196-A1 | Rare earth metal member of high surface purity and making method | Shin-Etsu Chemical Co., Ltd. (JP) | 2007-01-03 | — | — | EP | disclosed |
| US-6048396-A | Method for producing calcite-type calcium carbonate single crystal | TOYO DENKA KOGYO CO., LTD. (JP) | 2000-04-11 | — | — | US | disclosed |