SCHEMBL3457638

SCHEMBL3457638

CCn1cc[n+](Cc2ccccc2)c1C

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EEF2K O00418 2/20 0.70
EEF2 P13639 2/20 0.70
MEN1 O00255 1/20 0.70
PLK4 O00444 1/20 0.70
JAK2 O60674 1/20 0.70
EGFR P00533 1/20 0.70
TYK2 P29597 1/20 0.70
FLT3 P36888 1/20 0.70
BLM P54132 1/20 0.70
KMT2A Q03164 1/20 0.70
ITK Q08881 1/20 0.70
PIM2 Q9P1W9 1/20 0.70
CA1 P00915 9/20 0.69
CA2 P00918 9/20 0.69
TP53 P04637 1/20 0.40
LMNA P02545 2/20 0.39
KDM4E B2RXH2 2/20 0.39
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21698043 0.90 EEF2K (0.59) EEF2KEEF2MEN1PLK4JAK2
SCHEMBL5305200 0.88 EEF2K (0.78) EEF2KEEF2MEN1PLK4JAK2
SCHEMBL1078732 0.88 CA1 (0.74) EEF2KEEF2MEN1PLK4JAK2
Bromide SCHEMBL1044433 0.86 CA1 (0.72) EEF2KEEF2MEN1PLK4JAK2
SCHEMBL10325952 0.86 CA1 (0.77) EEF2KEEF2MEN1PLK4JAK2
Hydrochloric Acid SCHEMBL1877207 0.86 CA1 (0.77) EEF2KEEF2MEN1PLK4JAK2
Water SCHEMBL11782764 0.86 CA1 (0.72) EEF2KEEF2MEN1PLK4JAK2
SCHEMBL5307348 0.85 EEF2K (0.89) EEF2KEEF2MEN1PLK4JAK2
SCHEMBL5288997 0.84 EEF2K (0.97) EEF2KEEF2MEN1PLK4JAK2
SCHEMBL5291762 0.83 EEF2K (1.00) EEF2KEEF2MEN1PLK4JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100321863-A1 ACTIVATED CARBON AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-12-23 US disclosed
US-7785495-B2 Activated carbon prepared by carbonizing and activating a calixarene containing dihydroxybenzene rings; especially calcining at 400 degrees C. or less in the presence of an oxidative gas, calcining at 1500 degrees or less in an inactive gas, and then further calcining at 200-1500 degrees in H2O or CO2 SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-08-31 US disclosed
EP-2093191-A1 ACTIVATED CARBON AND METHOD FOR PRODUCING THE SAME Sumitomo Chemical Company, Limited (JP) 2009-08-26 EP disclosed
US-20090103241-A1 Activated carbon prepared by carbonizing and activating a calixarene containing dihydroxybenzene rings; especially calcining at 400 degrees C. or less in the presence of an oxidative gas, calcining at 1500 degrees or less in an inactive gas, and then further calcining at 200-1500 degrees in H2O or CO2 SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-04-23 US disclosed
EP-1905740-A1 ELECTRIC DOUBLE LAYER CAPACITOR Sumitomo Chemical Company, Limited (JP) 2008-04-02 EP disclosed
WO-2007006418-A1 IONIC-LIQUID-CONTAINING PRODUCTS FOR DYEING AND/OR BRIGHTENING KERATIN FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-01-18 WO disclosed
WO-2006131234-A1 COSMETIC COMPOSITIONS COMPRISING IONIC LIQUIDS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-12-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090103241-A1 Activated carbon prepared by carbonizing and activating a calixarene containing dihydroxybenzene rings; especially calcining at 400 degrees C. or less in the presence of an oxidative gas, calcining at 1500 degrees or less in an inactive gas, and then further calcining at 200-1500 degrees in H2O or CO2 CBR1, CYP24A1, CALU EEF2K 2992/4885EEF2 3396/4885MEN1 4643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.