Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.77 |
| ▸ | CA2 | P00918 | 6/20 | 0.77 |
| ▸ | EEF2K | O00418 | 2/20 | 0.62 |
| ▸ | EEF2 | P13639 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | PLK4 | O00444 | 1/20 | 0.62 |
| ▸ | JAK2 | O60674 | 1/20 | 0.62 |
| ▸ | EGFR | P00533 | 1/20 | 0.62 |
| ▸ | TYK2 | P29597 | 1/20 | 0.62 |
| ▸ | FLT3 | P36888 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | ITK | Q08881 | 1/20 | 0.62 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.62 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1078732 | 0.98 | CA1 (0.74) | CA1CA2EEF2KEEF2MEN1 | |
| Water SCHEMBL11782764 | 0.97 | CA1 (0.72) | CA1CA2EEF2KEEF2MEN1 | |
| Bromide SCHEMBL1044433 | 0.97 | CA1 (0.72) | CA1CA2EEF2KEEF2MEN1 | |
| SCHEMBL10325952 | 0.97 | CA1 (0.77) | CA1CA2EEF2KEEF2MEN1 | |
| Hydrochloric Acid SCHEMBL1179416 | 0.94 | CA1 (0.74) | CA1CA2EEF2KEEF2MEN1 | |
| Hydrochloric Acid SCHEMBL1179414 | 0.94 | CA1 (0.74) | CA1CA2EEF2KEEF2MEN1 | |
| SCHEMBL1044084 | 0.92 | CA1 (0.71) | CA1CA2EEF2KEEF2MEN1 | |
| SCHEMBL10325611 | 0.92 | CA1 (0.71) | CA1CA2EEF2KEEF2MEN1 | |
| SCHEMBL1044087 | 0.92 | CA1 (0.71) | CA1CA2EEF2KEEF2MEN1 | |
| SCHEMBL3457638 | 0.86 | EEF2K (0.70) | CA1CA2EEF2KEEF2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109957286-B | Printing ink and preparation method and application thereof | 深圳市百柔新材料技术有限公司 | 2021-11-23 | — | — | CN | claimed |
| CN-113352796-A | Environment-friendly printing process | 上海臻中印务科技有限公司 | 2021-09-07 | — | — | CN | claimed |
| US-3931129-A | FLUOROELASTOMER COMPOSITION | DAIKIN KOGYO CO., LTD. (JA) | 1976-01-06 | — | — | US | claimed |
| EP-4015545-B1 | ACRYLIC RUBBER, CROSSLINKABLE RUBBER COMPOSITION, AND RUBBER CURED PRODUCT | DENKA COMPANY LTD (JP) | 2024-05-29 | — | — | EP | disclosed |
| US-11939466-B2 | Thermoplastic polyester resin composition and molded article | TORAY INDUSTRIES, INC. (JP) | 2024-03-26 | — | — | US | disclosed |
| EP-3608366-B1 | THERMOPLASTIC POLYESTER RESIN COMPOSITION AND MOLDED ARTICLE | TORAY INDUSTRIES (JP) | 2024-03-06 | — | — | EP | disclosed |
| EP-3647367-B1 | THERMOPLASTIC POLYESTER RESIN COMPOSITION AND MOLDED ARTICLE THEREOF | TORAY INDUSTRIES (JP) | 2023-11-15 | — | — | EP | disclosed |
| EP-3854849-B1 | THERMOPLASTIC POLYESTER RESIN COMPOSITION AND MOLDED ARTICLE | TORAY INDUSTRIES (JP) | 2023-09-06 | — | — | EP | disclosed |
| CN-114174355-B | Acrylic rubber, crosslinkable rubber composition, and rubber cured product | 电化株式会社 | 2023-08-22 | — | — | CN | disclosed |
| EP-3805313-B1 | ACRYLIC ELASTOMER COMPOSITION | DENKA COMPANY LTD (JP) | 2023-05-03 | — | — | EP | disclosed |
| US-20220363793-A1 | ACRYLIC RUBBER, CROSSLINKABLE RUBBER COMPOSITION, AND RUBBER CURED PRODUCT | DENKA COMPANY LIMITED (JP) | 2022-11-17 | — | — | US | disclosed |
| EP-0328411-A2 | Composition for vibration damper, process for manufacture thereof, and vibration damper | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-08-16 | — | — | EP | disclosed |
| US-4767802-A | WITH FINE PARTICLES OF RUBBER CONTAINING SURFACE ADHERED INORGANIC MATERIAL, IMPROVED PEEL STRENGTH AND TOUGHNESS WHEN CURED | SUNSTAR GIKEN KABUSHIKI KAISHA (JP) | 1988-08-30 | — | — | US | disclosed |
| EP-0251760-A2 | Rubber composition | Bridgestone Corporation (JP) | 1988-01-07 | — | — | EP | disclosed |
| US-4501853-A | HEATING, STIRRING WITH LIQUID RUBBER, VULCANIZATION RUBBER TO GIVE DISPERSION | SUNSTAR GIKEN KABUSHIKI KAISHA (JP) | 1985-02-26 | — | — | US | disclosed |
| EP-0019435-B1 | A TANNING PROCESS AND TANNING COMPOSITIONS | SEITETSU KAGAKU CO., LTD. (JP) | 1984-03-21 | — | — | EP | disclosed |
| EP-0064761-A1 | Pickling and tanning process and pickling composition | SEITETSU KAGAKU CO., LTD. (JP) | 1982-11-17 | — | — | EP | disclosed |
| US-4348201-A | CHROMIUM OR ALUMINUM SALTS; UPGRADING; POLLUTION CONTROL; HIGH SPEED | SEITETSU KAGAKU CO., LTD. (JP) | 1982-09-07 | — | — | US | disclosed |
| EP-0019435-A2 | A tanning process and tanning compositions | SEITETSU KAGAKU CO., LTD. (JP) | 1980-11-26 | — | — | EP | disclosed |
| US-3931129-A | FLUOROELASTOMER COMPOSITION | DAIKIN KOGYO CO., LTD. (JA) | 1976-01-06 | — | — | US | disclosed |