Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | PRKCG | P05129 | 1/20 | 0.50 |
| ▸ | LYN | P07948 | 1/20 | 0.50 |
| ▸ | PRKACA | P17612 | 1/20 | 0.50 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.50 |
| ▸ | CLK2 | P49760 | 1/20 | 0.50 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.50 |
| ▸ | PRKX | P51817 | 1/20 | 0.50 |
| ▸ | NEK4 | P51957 | 1/20 | 0.50 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.50 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13540759 | 0.80 | NPC1 (0.60) | NPC1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL1913680 | 0.78 | NPC1 (0.71) | ROCK2MAP4K4PRKCGLYNPRKACA | |
| SCHEMBL221983 | 0.76 | SMN1; SMN2 (0.60) | NPC1RAB9AKMT2AMEN1LMNA | |
| SCHEMBL14896793 | 0.74 | HRH3 (0.38) | NPC1RAB9AKMT2AKDM4ELMNA | |
| SCHEMBL5749417 | 0.70 | NPC1 (0.47) | NPC1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL23965805 | 0.70 | NPC1 (0.60) | DYRK1ANPC1RAB9AKMT2AMEN1 | |
| SCHEMBL15221710 | 0.70 | CDC7 (0.41) | CDC7 | |
| SCHEMBL14237602 | 0.69 | FABP1 (0.57) | MAP4K4CLK4NPC1RAB9AKMT2A | |
| SCHEMBL5467090 | 0.69 | RORC (0.49) | NPC1RAB9AKMT2AMEN1LMNA | |
| SCHEMBL1017978 | 0.69 | KMT2A (0.51) | NPC1RAB9AKMT2AMEN1FABP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010435-A2 | FUSED OXAZOLE AND THIAZOLE DERIVATIVES AS TRPMS MODULATORS | GLENMARK PHARMACEUTICAL S.A. (CH) | 2010-01-28 | — | — | WO | disclosed |