Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 11/20 | 0.59 |
| ▸ | BCHE | P06276 | 10/20 | 0.59 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3945832 | 0.77 | ACHE (0.50) | ACHEBCHEFAAHMARK4 | |
| SCHEMBL2800673 | 0.77 | ACHE (0.50) | ACHEBCHEFAAHMARK4 | |
| SCHEMBL5914311 | 0.75 | MEN1 (0.47) | ADRA2BADRA2CSLC6A2HTR2ASLC6A4 | |
| SCHEMBL533690 | 0.74 | ACHE (1.00) | ACHEBCHEFAAHMARK4 | |
| SCHEMBL7904941 | 0.74 | ACHE (1.00) | ACHEBCHEFAAHMARK4 | |
| SCHEMBL533689 | 0.74 | ACHE (1.00) | ACHEBCHEFAAHMARK4 | |
| SCHEMBL12557213 | 0.74 | ACHE (1.00) | ACHEBCHEFAAHMARK4 | |
| Hydrochloric Acid SCHEMBL1665699 | 0.74 | MEN1 (0.46) | ACHEBCHEADRA2BADRA2CSLC6A2 | |
| SCHEMBL12208527 | 0.73 | ACHE (0.72) | ACHEBCHEFAAHMARK4 | |
| SCHEMBL16103423 | 0.73 | ACHE (0.48) | ACHEBCHEHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100256229-A1 | COMPOSITIONS OF CHOLINESTERASE INHIBITORS | COLUCID PHARMACEUTICALS, INC. (US) | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256229-A1 | COMPOSITIONS OF CHOLINESTERASE INHIBITORS | ACHE, BCHE, CES1 | ACHE 1/4885BCHE 2/4885ADRA2B 2911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.