Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4101136 | 0.79 | CES2 (0.52) | CES2CES1TRPM8 | |
| SCHEMBL4099522 | 0.79 | CES2 (0.52) | CES2CES1TRPM8 | |
| SCHEMBL2001602 | 0.79 | CES2 (0.52) | CES2CES1TRPM8 | |
| SCHEMBL9945882 | 0.74 | CES2 (0.50) | CES2CES1TRPM8 | |
| SCHEMBL28266437 | 0.73 | CES2 (0.53) | CES2CES1TRPM8 | |
| SCHEMBL23046930 | 0.71 | CES2 (0.43) | CES2CES1TRPM8 | |
| SCHEMBL17043179 | 0.71 | CES2 (0.43) | CES2CES1TRPM8 | |
| SCHEMBL28268019 | 0.71 | CES2 (0.52) | CES2CES1TRPM8 | |
| SCHEMBL22646661 | 0.71 | CES2 (0.43) | CES2CES1TRPM8 | |
| SCHEMBL31050924 | 0.71 | CES2 (0.43) | CES2CES1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262807-A1 | NOVEL TYROSINE KINASE INHIBITORS | ChemBridge Corporation (US) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009117097-A1 | NOVEL TYROSINE KINASE INHIBITORS | CHEMBRIDGE CORPORATION (US) | 2009-09-24 | — | — | WO | disclosed |