Terephthalic Acid

Terephthalic Acid

SCHEMBL3460105

O=C(O)c1ccc(C(=O)O)cc1.Oc1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1

The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 1.00
CA1 P00915 3/20 1.00
CA12 O43570 1/20 1.00
CA3 P07451 1/20 1.00
TYR P14679 1/20 1.00
DRD1 P21728 1/20 1.00
CA4 P22748 1/20 1.00
CA6 P23280 1/20 1.00
CA5A P35218 1/20 1.00
CA7 P43166 1/20 1.00
CA9 Q16790 1/20 1.00
CA14 Q9ULX7 1/20 1.00
CA5B Q9Y2D0 1/20 1.00
SRD5A2 P31213 3/20 0.84
TSHR P16473 3/20 0.75
TP53 P04637 1/20 0.75
ESR1 P03372 1/20 0.63
ESR2 Q92731 1/20 0.63
LMNA P02545 1/20 0.63
MAPT P10636 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Paraben SCHEMBL3212865 1.00 CA2 (1.00) CA2CA1CA12CA3TYR
Paraben SCHEMBL5311518 1.00 CA2 (1.00) CA2CA1CA12CA3TYR
Paraben SCHEMBL4110 1.00 CA2 (1.00) CA2CA1CA12CA3TYR
Paraben SCHEMBL7622776 1.00 CA2 (1.00) CA2CA1CA12CA3TYR
Terephthalic Acid SCHEMBL6692916 1.00 CA2 (1.00) CA2CA1CA12CA3TYR
Paraben SCHEMBL20500516 1.00 CA2 (1.00) CA2CA1CA12CA3TYR
Paraben SCHEMBL1010571 0.97 CA2 (0.94) CA2CA1CA12CA3TYR
Paraben SCHEMBL21061691 0.97 CA2 (0.94) CA2CA1CA12CA3TYR
Paraben SCHEMBL10606180 0.97 CA2 (0.94) CA2CA1CA12CA3TYR
Paraben SCHEMBL20815891 0.97 CA2 (0.94) CA2CA1CA12CA3TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118773756-A Winding mechanism for preparing polypropylene filaments and method for preparing filaments by using winding mechanism 扬州市奕轩纤维有限公司 2024-10-15 CN claimed
CN-110181829-A A kind of liquid crystal polyester thin film industrial manufacture process 陈祚 2019-08-30 CN claimed
US-5948864-A BLENDS ACUSHNET COMPANY (US) 1999-09-07 US claimed
WO-1999040977-A1 GOLF BALL INCORPORATING LIQUID CRYSTALLINE POLYMERS ACUSHNET COMPANY (US) 1999-08-19 WO claimed
US-4962163-A ADVANCED POLYEPOXIDES AND EPOXY RESINS MODIFIED BY AN UNSATURATED CARBOXYLIC ACID; CURED COATING AND FILMS HAVINGI IMPROVED TENSILE AND FLEXURAL STRENGTH AND MODULUS THE DOW CHEMICAL COMPANY (US) 1990-10-09 US claimed
US-4837284-A HEAT, SOLVENT, CHEMICAL RESISTANCE AMOCO CORPORATION (US) 1989-06-06 US claimed
CN-112316559-B Cleanable filter media 约翰斯曼维尔公司 2024-11-26 CN disclosed
CN-118773756-A Winding mechanism for preparing polypropylene filaments and method for preparing filaments by using winding mechanism 扬州市奕轩纤维有限公司 2024-10-15 CN disclosed
US-20230383471-A1 ABSORBENT PAPER PRODUCTS HAVING UNIQUE PHYSICAL STRENGTH PROPERTIES MERCER INTERNATIONAL INC (CA) 2023-11-30 US disclosed
US-20230323606-A1 ABSORBENT PAPER PRODUCTS HAVING UNIQUE PHYSICAL STRENGTH PROPERTIES MERCER INTERNATIONAL INC (CA) 2023-10-12 US disclosed
US-11674267-B2 Absorbent paper products having unique physical strength properties MERCER INTERNATIONAL INC. (CA) 2023-06-13 US disclosed
US-11668053-B2 Absorbent paper products having unique physical strength properties MERCER INTERNATIONAL INC. (CA) 2023-06-06 US disclosed
CN-110612140-B Hemostatic valve and methods of making and using same 波士顿科学有限公司 2022-10-18 CN disclosed
US-5189117-A Tensile strength, tear strength, waterproofing THE DOW CHEMICAL COMPANY (US) 1993-02-23 US disclosed
US-5164464-A Liquid crystalline polymers, acrylated epoxy resins THE DOW CHEMICAL COMPANY (US) 1992-11-17 US disclosed
US-5118782-A THERMOTROPIC AROMATIC POLYESTER WHICH IS MELT-PROCESSABLE AT LOW TEMPERATURES AND EXHIBITS LIQUID CRYSTALLINE PROPERTIES UBE INDUSTRIES, LTD. (JP) 1992-06-02 US disclosed
US-5066750-A Addition polymers with pendant phenyl groups which can be oriented like liquid crystals THE DOW CHEMICAL COMPANY (US) 1991-11-19 US disclosed
EP-0417651-A2 Thermotropic aromatic polyester UBE INDUSTRIES, LTD. (JP) 1991-03-20 EP disclosed
US-4962163-A ADVANCED POLYEPOXIDES AND EPOXY RESINS MODIFIED BY AN UNSATURATED CARBOXYLIC ACID; CURED COATING AND FILMS HAVINGI IMPROVED TENSILE AND FLEXURAL STRENGTH AND MODULUS THE DOW CHEMICAL COMPANY (US) 1990-10-09 US disclosed
EP-0379058-A2 Vinyl ester resins containing mesogenic/rigid rodlike moieties THE DOW CHEMICAL COMPANY (US) 1990-07-25 EP disclosed