SCHEMBL34604

SCHEMBL34604

CC1(C)OC[C@H]([C@@H](CS(=O)(=O)c2ccc(Oc3ccc(OC(F)(F)F)cc3)cc2)N(O)C=O)O1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MMP9 P14780 20/20 1.00
MMP2 P08253 17/20 1.00
MMP1 P03956 9/20 1.00
MMP3 P08254 1/20 1.00
MMP7 P09237 1/20 1.00
MMP8 P22894 1/20 1.00
MMP13 P45452 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7594373 1.00 MMP9 (1.00) MMP9MMP2MMP1MMP3MMP7
SCHEMBL8341893 1.00 MMP9 (1.00) MMP9MMP2MMP1MMP3MMP7
SCHEMBL7429119 1.00 MMP9 (1.00) MMP9MMP2MMP1MMP3MMP7
SCHEMBL7594723 1.00 MMP9 (1.00) MMP9MMP2MMP1MMP3MMP7
SCHEMBL7429131 1.00 MMP9 (1.00) MMP9MMP2MMP1MMP3MMP7
SCHEMBL7594720 1.00 MMP9 (1.00) MMP9MMP2MMP1MMP3MMP7
SCHEMBL13035001 0.92 MMP9 (0.85) MMP9MMP2MMP1MMP3MMP7
SCHEMBL7593382 0.91 MMP9 (0.84) MMP9MMP2MMP1MMP3MMP7
SCHEMBL7593375 0.91 MMP9 (0.84) MMP9MMP2MMP1MMP3MMP7
SCHEMBL7594936 0.90 MMP9 (1.00) MMP9MMP2MMP1MMP3MMP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1147101-B1 REVERSE HYDROXAMATE INHIBITORS OF MATRIX METALLOPROTEINASES ABBOTT LAB (US) 2002-11-20 EP claimed
US-11718877-B2 Methods for use in the diagnosis of autoimmune diseases THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) 2023-08-08 US disclosed
US-20220288086-A1 TREATMENT FOR BACTERIAL INFECTION VYOME THERAPEUTICS LIMITED (IN) 2022-09-15 US disclosed
US-9296011-B2 Prosthesis having varied concentration of beneficial agent ABBOTT LABORATORIES (US) 2016-03-29 US disclosed
US-9296011-B2 Prosthesis having varied concentration of beneficial agent ABBOTT LABORATORIES (US) 2016-03-29 US disclosed
US-20150196692-A1 MULTIPLE DRUG DELIVERY FROM A BALLOON AND A PROSTHESIS ABBOTT LABORATORIES (US) 2015-07-16 US disclosed
US-20150112425-A1 DELIVERY OF HIGHLY LIPOPHILIC AGENTS VIA MEDICAL DEVICES ABBOTT LAB (US) 2015-04-23 US disclosed
US-20150112425-A1 DELIVERY OF HIGHLY LIPOPHILIC AGENTS VIA MEDICAL DEVICES ABBOTT LAB (US) 2015-04-23 US disclosed
US-8956639-B2 Multiple drug delivery from a balloon and prosthesis ABBOTT LABORATORIES (US) 2015-02-17 US disclosed
US-8956639-B2 Multiple drug delivery from a balloon and prosthesis ABBOTT LABORATORIES (US) 2015-02-17 US disclosed
US-20070110280-A1 Methods for Determining Coating Thickness of a Prosthesis ABBOTT LABORATORIES 2007-05-17 US disclosed
US-7208190-B2 Method of loading beneficial agent to a prosthesis by fluid-jet application ABBOTT LABORATORIES (US) 2007-04-24 US disclosed
US-7208190-B2 Method of loading beneficial agent to a prosthesis by fluid-jet application ABBOTT LABORATORIES (US) 2007-04-24 US disclosed
US-20070088255-A1 METHOD OF TREATING VASCULAR DISEASE AT A BIFURCATED VESSEL USING A COATED BALLOON TONER JOHN L 2007-04-19 US disclosed
US-20070088255-A1 METHOD OF TREATING VASCULAR DISEASE AT A BIFURCATED VESSEL USING A COATED BALLOON TONER JOHN L 2007-04-19 US disclosed
US-20070053953-A1 Method of loading beneficial agent to a prosthesis by fluid-jet application VERLEE DONALD 2007-03-08 US disclosed
US-20070053953-A1 Method of loading beneficial agent to a prosthesis by fluid-jet application VERLEE DONALD 2007-03-08 US disclosed
US-20070027523-A1 Method of treating vascular disease at a bifurcated vessel using coated balloon ABBOTT LABORATORIES 2007-02-01 US disclosed
US-20070027523-A1 Method of treating vascular disease at a bifurcated vessel using coated balloon ABBOTT LABORATORIES 2007-02-01 US disclosed
EP-1147101-B1 REVERSE HYDROXAMATE INHIBITORS OF MATRIX METALLOPROTEINASES ABBOTT LAB (US) 2002-11-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220288086-A1 TREATMENT FOR BACTERIAL INFECTION ELANE, CFTR, TLR5 MMP9 1320/4885MMP2 429/4885MMP1 215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.