SCHEMBL346178

SCHEMBL346178

[O]C1=CC=CN2CC=CC=C12

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11312341 0.75
SCHEMBL6423804 0.75
SCHEMBL3547579 0.75
SCHEMBL18186102 0.75
SCHEMBL9853417 0.72
SCHEMBL8576907 0.71
SCHEMBL28195334 0.71
SCHEMBL8518034 0.71
SCHEMBL9693368 0.71
SCHEMBL11090349 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4214200-A1 LANCL LIGANDS Nimmune Biopharma, Inc. (US) 2023-07-26 EP disclosed
CN-113748109-B Lanthionine C-like protein 2 ligands, cells prepared with said ligands and therapies using said ligands 朗多生物制药股份有限公司 2023-07-21 CN disclosed
CN-116368133-A NLRX1 ligand 朗多生物制药股份有限公司 2023-06-30 CN disclosed
US-20230167083-A1 LANCL LIGANDS LANDOS BIOPHARMA, INC. (US) 2023-06-01 US disclosed
US-11459310-B2 LANCL ligands LANDOS BIOPHARMA, INC. (US) 2022-10-04 US disclosed
WO-2022087146-A1 LANCL LIGANDS LANDOS BIOPHARMA, INC. (US) 2022-04-28 WO disclosed
US-20220127250-A1 LANCL LIGANDS LANDOS BIOPHARMA, INC. (US) 2022-04-28 US disclosed
CN-113748109-A Lanthionine C-like protein 2 ligands, cells prepared with said ligands and therapies using said ligands 朗多生物制药股份有限公司 2021-12-03 CN disclosed
EP-2266978-B1 Novel physiologically active substances EISAI R&D MAN CO LTD (JP) 2015-05-20 EP disclosed
EP-1548121-B1 Physiologically active substances EISAI R&D MAN CO LTD (JP) 2015-04-29 EP disclosed
US-20060241171-A1 Novel physiologically active substances MICROBIOPHARM JAPAN CO., LTD. (JP) 2006-10-26 US disclosed
US-20060235002-A1 Novel physiologically active substance EISAI R&D MANAGEMENT CO., LTD. (JP) 2006-10-19 US disclosed
EP-1710244-A1 METHOD OF STABILIZING MACROLIDE COMPOUND Eisai R&D Management Co., Ltd. (JP) 2006-10-11 EP disclosed
EP-1705247-A1 DNA PARTICIPATING IN HYDROXYLATION OF MACROLIDE COMPOUND MERCIAN CORPORATION (JP) 2006-09-27 EP disclosed
US-20060009439-A1 Novel physiologically active substances MERCIAN CORPORATION (JP) 2006-01-12 US disclosed
US-20050245514-A1 Novel physiologically active substances MICROBIOPHARM JAPAN CO., LTD. (JP) 2005-11-03 US disclosed
US-20050227959-A1 Heterocyclic compound having oxime group EISAI CO., LTD. (JP) 2005-10-13 US disclosed
EP-1548121-A1 NOVEL PHYSIOLOGICALLY ACTIVE SUBSTANCES MERCIAN CORPORATION (JP) 2005-06-29 EP disclosed
EP-1541570-A1 NOVEL PHYSIOLOGICALLY ACTIVE SUBSTANCE MERCIAN CORPORATION (JP) 2005-06-15 EP disclosed
EP-1508570-A1 NOVEL PHYSIOLGICALLY ACTIVE SUBSTANCES MERCIAN CORPORATION (JP) 2005-02-23 EP disclosed