⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11312341 | 0.72 | — | — | |
| SCHEMBL6423804 | 0.68 | — | — | |
| SCHEMBL7789814 | 0.68 | KMT2A (0.32) | — | |
| SCHEMBL28060781 | 0.66 | NPC1 (0.36) | — | |
| SCHEMBL418353 | 0.66 | ABCB11 (0.30) | — | |
| SCHEMBL7798350 | 0.64 | ALDH1A1 (0.32) | — | |
| SCHEMBL8518034 | 0.64 | — | — | |
| SCHEMBL2049800 | 0.63 | MAPT (0.33) | — | |
| SCHEMBL3793801 | 0.63 | CRHBP (0.34) | — | |
| SCHEMBL4140323 | 0.62 | MAPT (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044573-B1 | 7-PHENYLQUINOLIZINE | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-02-29 | — | — | EP | claimed |
| EP-0044573-A1 | 7-Phenylquinolizine | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-01-27 | — | — | EP | claimed |
| EP-0044573-B1 | 7-PHENYLQUINOLIZINE | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-02-29 | — | — | EP | disclosed |
| EP-0044573-A1 | 7-Phenylquinolizine | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-01-27 | — | — | EP | disclosed |
| EP-0044573-A1 | 7-Phenylquinolizine | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-01-27 | — | — | EP | disclosed |