Cyclopropane

Cyclopropane

SCHEMBL3461994

C1CC1.CO[Si](CC1CO1)(OC)OC

nearest known ligand 0.33

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Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
TSHR P16473 2/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27731585 0.95 ALDH1A1 (0.36) ALDH1A1TSHRMAPK1TDP1SMN1; SMN2
SCHEMBL198113 0.95 ALDH1A1 (0.36) ALDH1A1TSHRMAPK1TDP1SMN1; SMN2
SCHEMBL662055 0.86 ALDH1A1 (0.33) ALDH1A1TSHRMAPK1TDP1SMN1; SMN2
SCHEMBL20242004 0.83 SMN1; SMN2 (0.31) SMN1; SMN2
SCHEMBL7519519 0.77
SCHEMBL27783081 0.77
SCHEMBL5187800 0.77 ALDH1A1 (0.66) ALDH1A1TDP1SMN1; SMN2
SCHEMBL28165102 0.76 EPHX1 (0.35)
SCHEMBL8675890 0.76 ALDH1A1 (0.32) ALDH1A1
SCHEMBL3068447 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7807013-B2 Tie-layer materials, articles and methods for making and using same FIBERSPAR CORPORATION (US) 2010-10-05 US disclosed
US-20090090460-A1 Tie-Layer Materials, Articles and Methods for Making and Using Same RBS CITIZENS, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT 2009-04-09 US disclosed
US-7285333-B2 Tie-layer materials, articles and methods for making and using same FIBERSPAR CORPORATION (US) 2007-10-23 US disclosed
US-20040265524-A1 Tie-layer materials, articles and methods for making and using same FIBERSPAR CORPORATION 2004-12-30 US disclosed