SCHEMBL346202

SCHEMBL346202

O=c1[nH]cc([C@H]2C[C@H](O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]1

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
POLA1 P09884 2/20 0.42
POLB P06746 2/20 0.41
POLD1 P28340 1/20 0.41
P2RY2 P41231 7/20 0.41
P2RY6 Q15077 2/20 0.41
P2RY4 P51582 5/20 0.41
TYMS P04818 2/20 0.39
P2RX3 P56373 1/20 0.39
DUT P33316 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15810868 0.91 TYMS (0.39) POLBTYMSDUT
SCHEMBL15810851 0.90 P2RY2 (0.42) POLA1POLBPOLD1P2RY2P2RY6
SCHEMBL2888800 0.89 TYMS (0.48) TYMS
SCHEMBL15810739 0.81 POLA1 (0.39) POLA1POLBPOLD1P2RY2P2RY6
SCHEMBL21277514 0.81 P2RY2 (0.51) P2RY2P2RY6P2RY4P2RX3
SCHEMBL24414862 0.81 P2RY2 (0.51) P2RY2P2RY6P2RY4P2RX3
SCHEMBL15810759 0.81 P2RY2 (0.51) P2RY2P2RY6P2RY4P2RX3
SCHEMBL21277384 0.81 P2RY2 (0.51) P2RY2P2RY6P2RY4P2RX3
SCHEMBL15810760 0.81 P2RY2 (0.51) P2RY2P2RY6P2RY4P2RX3
SCHEMBL625518 0.81 P2RY2 (0.51) P2RY2P2RY6P2RY4P2RX3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12509716-B2 Functional ligands to target vitamin C Base Pair Biotechnologies, Inc. (US) 2025-12-30 US disclosed
US-12338434-B1 Methods and materials for discovery of functional ligands to molecular complexes Base Pair Biotechnologies, Inc. (US) 2025-06-24 US disclosed
US-11970785-B2 Methods and materials for multiplexed collections of functional ligands Base Pair Biotechnologies, Inc. (US) 2024-04-30 US disclosed
US-20240110237-A1 FUNCTIONAL LIGANDS BASE PAIR BIOTECHNOLOGIES INC (US) 2024-04-04 US disclosed
US-11725240-B2 Functional ligands to opioids and opioid derivatives Base Pair Biotechnologies, Inc. (US) 2023-08-15 US disclosed
CN-116472276-A Cytosine-type cross-linked nucleoside phosphoramidite crystal and method for producing same 雅玛山酱油株式会社 2023-07-21 CN disclosed
US-20230111624-A1 FUNCTIONAL LIGANDS TO TARGET MOLECULES BASE PAIR BIOTECHNOLOGIES INC (US) 2023-04-13 US disclosed
US-11608356-B1 Functional ligands to colistin Base Pair Biotechnologies, Inc. (US) 2023-03-21 US disclosed
US-20220396795-A1 FUNCTIONAL LIGANDS TO SARS-COV-2 SPIKE PROTEIN BASE PAIR BIOTECHNOLOGIES INC (US) 2022-12-15 US disclosed
US-11427825-B2 Functional ligands to drug compounds Base Pair Biotechnologies, Inc. (US) 2022-08-30 US disclosed
US-20120121533-A1 NUCLEIC ACID LIGANDS TO LL37 BIOTEX, INC. (US) 2012-05-17 US disclosed
US-20120015359-A1 METHODS FOR MOLECULAR DETECTION BIOTEX, INC. (US) 2012-01-19 US disclosed
US-20110306054-A1 METHODS FOR MOLECULAR DETECTION BIOTEX, INC. (US) 2011-12-15 US disclosed
US-8034569-B2 Methods for molecular detection BIOTEX, INC. (US) 2011-10-11 US disclosed
US-20100240550-A1 METHODS FOR SIMULTANEOUS GENERATION OF FUNCTIONAL LIGANDS BIOTEX, INC. (US) 2010-09-23 US disclosed
US-20100003688-A1 METHODS FOR MOLECULAR DETECTION BIOTEX, INC. (US) 2010-01-07 US disclosed
US-20090275130-A1 BIOMIMETIC NUCLEIC ACIDS BIOTEX, INC. (US) 2009-11-05 US disclosed
EP-0815117-B1 C-NUCLEOSIDE DERIVATIVES AND THEIR USE IN NUCLEIC ACID DETECTION ROCHE DIAGNOSTICS GMBH (DE) 2002-01-02 EP disclosed
US-6320035-B1 OLIGONUCLEOTIDE SYNTHESIZED FROM SPECIFIED NUCLEOSIDES HAVING AT LEAST ONE REPORTER GROUP BOUND TO PYRIMIDINE OR FURANOSE RING VIA LINKER GROUP WHICH CONTAINS ALKYNYL GROUP ROCHE DIAGNOSTICS GMBH (DE) 2001-11-20 US disclosed
US-6174998-B1 FOR LABELLING AND DNA SEQUENCING ROCHE DIAGNOSTICS GMBH (DE) 2001-01-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509716-B2 Functional ligands to target vitamin C PROC, HMOX2, H1-2 POLA1 2495/4885POLB 2732/4885POLD1 2936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.