Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OSBP | P22059 | 1/20 | 0.78 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.78 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.76 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.76 |
| ▸ | ST6GAL1 | P15907 | 2/20 | 0.75 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.74 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.72 |
| ▸ | CASP7 | P55210 | 3/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.72 |
| ▸ | TP53 | P04637 | 2/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.72 |
| ▸ | BLM | P54132 | 2/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.72 |
| ▸ | VDR | P11473 | 2/20 | 0.72 |
| ▸ | USP2 | O75604 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.72 |
| ▸ | MDM4 | O15151 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Epicoprosterol SCHEMBL11375007 | 1.00 | OSBP (0.78) | OSBPOSBP2CYP2C19CYP2D6ST6GAL1 | |
| Epicoprosterol SCHEMBL10066473 | 1.00 | OSBP (0.78) | OSBPOSBP2CYP2C19CYP2D6ST6GAL1 | |
| Epicoprosterol SCHEMBL18724866 | 1.00 | OSBP (0.78) | OSBPOSBP2CYP2C19CYP2D6ST6GAL1 | |
| Epicoprosterol SCHEMBL9906585 | 1.00 | OSBP (0.78) | OSBPOSBP2CYP2C19CYP2D6ST6GAL1 | |
| Epicoprosterol SCHEMBL24632942 | 1.00 | OSBP (0.78) | OSBPOSBP2CYP2C19CYP2D6ST6GAL1 | |
| Epicoprosterol SCHEMBL12549295 | 1.00 | OSBP (0.78) | OSBPOSBP2CYP2C19CYP2D6ST6GAL1 | |
| Epicoprosterol SCHEMBL25267973 | 1.00 | OSBP (0.78) | OSBPOSBP2CYP2C19CYP2D6ST6GAL1 | |
| Epicoprosterol SCHEMBL12214992 | 1.00 | OSBP (0.78) | OSBPOSBP2CYP2C19CYP2D6ST6GAL1 | |
| Epicoprosterol SCHEMBL21000320 | 1.00 | OSBP (0.78) | OSBPOSBP2CYP2C19CYP2D6ST6GAL1 | |
| Epicoprosterol SCHEMBL22018677 | 1.00 | OSBP (0.78) | OSBPOSBP2CYP2C19CYP2D6ST6GAL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427773-B1 | METHOD OF DIAGNOSING ASPHYXIA | INFANDX AG (DE) | 2016-07-06 | — | — | EP | disclosed |
| EP-2249161-A1 | Method of diagnosing asphyxia | BIOCRATES Life Sciences AG (AT) | 2010-11-10 | — | — | EP | disclosed |