⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15941914 | 0.93 | — | — | |
| SCHEMBL4503067 | 0.90 | — | — | |
| SCHEMBL8769955 | 0.82 | — | — | |
| SCHEMBL973460 | 0.82 | — | — | |
| SCHEMBL223825 | 0.79 | — | — | |
| Bromide SCHEMBL28242864 | 0.78 | — | — | |
| SCHEMBL10179319 | 0.75 | TSHR (0.36) | — | |
| SCHEMBL8769971 | 0.73 | — | — | |
| SCHEMBL1062616 | 0.73 | — | — | |
| SCHEMBL2520528 | 0.70 | MAPT (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240101590-A1 | METHOD FOR THE SITE-SPECIFIC ENZYMATIC LABELLING OF NUCLEIC ACIDS IN VITRO BY INCORPORATION OF UNNATURAL NUCLEOTIDES | THE SCRIPPS RESEARCH INSTITUTE | 2024-03-28 | — | — | US | disclosed |
| US-11634451-B2 | Method for the site-specific enzymatic labelling of nucleic acids in vitro by incorporation of unnatural nucleotides | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-04-25 | — | — | US | disclosed |
| US-11608323-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2023-03-21 | — | — | US | disclosed |
| EP-3054773-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-01-26 | — | — | EP | disclosed |
| EP-3656781-A1 | A METHOD FOR THE SITE-SPECIFIC ENZYMATIC LABELLING OF NUCLEIC ACIDS IN VITRO BY INCORPORATION OF UNNATURAL NUCLEOTIDES | The Scripps Research Institute (US) | 2020-05-27 | — | — | EP | disclosed |
| US-10653143-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-19 | — | — | US | disclosed |
| US-10626138-B2 | Method for the site-specific enzymatic labelling of nucleic acids in vitro by incorporation of unnatural nucleotides | THE SCRIPPS RESEARCH INSTITUTE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT OF HEALTH AND HUMAN SERVICES (DHHS) (US) | 2020-04-21 | — | — | US | disclosed |
| US-20200040027-A1 | A METHOD FOR THE SITE-SPECIFIC ENZYMATIC LABELLING OF NUCLEIC ACIDS IN VITRO BY INCORPORATION OF UNNATURAL NUCLEOTIDES | THE SCRIPPS RESEARCH INSTITUTE | 2020-02-06 | — | — | US | disclosed |
| US-10499640-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2019-12-10 | — | — | US | disclosed |
| EP-3154965-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-05-08 | — | — | EP | disclosed |
| US-20020034774-A1 | Treatment or prophylaxis of diseases caused by pilus-forming bacteria | HULTGREN SCOTT (US) | 2002-03-21 | — | — | US | disclosed |
| US-6153396-A | DRUG SCREENING BY ADDING COMPOUND TO MIXTURE OF CHAPERONE AND PILUS SUBUNIT AND DETERMINING THE CHANGE IN BINDING; BACTERICIDES FOR URINARY TRACT INFECTIONS | SIGA PHARMACEUTICALS, INC. (US) | 2000-11-28 | — | — | US | disclosed |
| US-6001823-A | NOVEL PYRANOSIDES WHICH ARE BELIEVED TO BE CAPABLE OF INTERACTING WITH PERIPLASMIC MOLECULAR CHAPERONES | WASHINGTON UNIVERSITY | 1999-12-14 | — | — | US | disclosed |
| EP-0730601-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTIONS | WASHINGTON UNIVERSITY (US) | 1996-09-11 | — | — | EP | disclosed |
| EP-0725563-A1 | MARINE STRUCTURE | J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) | 1996-08-14 | — | — | EP | disclosed |
| WO-1995014028-A9 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTIONS | — | 1995-08-10 | — | — | WO | disclosed |
| WO-1995014028-A2 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTIONS | WASHINGTON UNIVERSITY (US) | 1995-05-26 | — | — | WO | disclosed |
| WO-1995011592-A1 | MARINE STRUCTURE | J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) | 1995-05-04 | — | — | WO | disclosed |
| EP-0178139-B1 | PROCESS FOR PRODUCING 2,3-DISUBSTITUTED -4-SUBSTITUTED CYCLOPENTANONES, ENANTIOMORPHS, OR MIXTURES THEREOF | TEIJIN LIMITED (JP) | 1989-07-05 | — | — | EP | disclosed |
| US-4297492-A | STABILIZERS FOR PLASTICS | CIBA-GEIGY CORPORATION (US) | 1981-10-27 | — | — | US | disclosed |