SCHEMBL223825

SCHEMBL223825

[C]#CCCC#C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15941914 0.79
SCHEMBL3462993 0.79
SCHEMBL5964839 0.78
SCHEMBL111375 0.78
SCHEMBL4503067 0.76
Phosphine SCHEMBL11421364 0.74
SCHEMBL9812478 0.74
Ammonia Solution, Strong SCHEMBL11048819 0.74
Inositol SCHEMBL18335516 0.69 LMNA (0.39)
SCHEMBL10179319 0.68 TSHR (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 929 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12042479-B2 Use of topical formulations of cannabinoids in the treatment of epidermolysis bullosa and related connective tissue disorders INMED PHARMACEUTICALS INC. 2024-07-23 US disclosed
US-20240239751-A1 PROCESSES FOR PREPARING AG-10, ITS INTERMEDIATES, AND SALTS THEREOF BRIDGEBIO GENE THERAPY RESEARCH, INC. 2024-07-18 US disclosed
US-20240238427-A1 METHODS OF TREATING AN EYE DISORDER KODIAK SCIENCES INC. 2024-07-18 US disclosed
US-20240239807-A1 SARS-COV2 MAIN PROTEASE INHIBITORS GILEAD SCIENCES, INC. 2024-07-18 US disclosed
CN-118344348-A Heterocyclic substituted quinazoline and preparation method and application thereof 苏州泽璟生物制药股份有限公司 2024-07-16 CN disclosed
US-20240228480-A1 PROCESSES FOR PREPARING PYRROLOPYRIDINE-ANILINE COMPOUNDS CURIA GLOBAL, INC. 2024-07-11 US disclosed
US-20240218011-A1 GLUCOCORTICOID RECEPTOR AGONISTS AND CONJUGATES THEREOF FIREFLY BIO, INC. 2024-07-04 US disclosed
US-20240218021-A1 CYCLIN INHIBITORS CIRCLE PHARMA, INC. 2024-07-04 US disclosed
US-12024731-B2 Methods and enzyme catalysts for the synthesis of non-canonical amino acids CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2024-07-02 US disclosed
US-20240208973-A1 TETRACYCLIC COMPOUNDS FOR TREATING BRAIN DISORDERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2024-06-27 US disclosed
EP-1409466-A2 HIV PROTEASE INHIBITORS, COMPOSITIONS CONTAINING THE SAME, THEIR PHARMACEUTICAL USES AND MATERIALS FOR THEIR SYNTHESIS AGOURON PHARMACEUTICALS, INC. (US) 2004-04-21 EP disclosed
US-6693090-B2 OSTEOPOROSIS AVENTIS PHARMA S.A. (FR) 2004-02-17 US disclosed
US-20030225071-A1 HIV protease inhibitors, compositions containing the same, their pharmaceutical uses and materials for their synthesis PFIZER INC. 2003-12-04 US disclosed
US-20030153507-A1 HIV protease inhibitors, compositions containing the same, their pharmaceutical uses and materials for their synthesis AGOURON PHARMACEUTICALS, INC. 2003-08-14 US disclosed
US-20030073675-A1 Novel 19-norsteroids substituted in position 11beta, preparation process and intermediates, application as medicines and pharmaceutical compositions containing them AVENTIS PHARMA S.A. 2003-04-17 US disclosed
WO-2002100844-A2 HIV PROTEASE INHIBITORS, COMPOSITIONS CONTAINING THE SAME, THEIR PHARMACEUTICAL USES AND MATERIALS FOR THEIR SYNTHESIS AGOURON PHARMACEUTICALS, INC. (US) 2002-12-19 WO disclosed
WO-2002100845-A1 HV PROTEASE INHIBITORS, COMPOSITIONS CONTAINING THE SAME, THEIR PHARMACEUTICAL USES AND MATERIALS FOR THEIR SYNTHESIS AGOURON PHARMACEUTICALS, INC. (US) 2002-12-19 WO disclosed
US-6479476-B1 TREATING MENOPAUSAL SYMPTOMS AND OSTEOPOROSIS IN FEMALE WARM-BLOODED ANIMALS AVENTIS PHARMA S.A. (FR) 2002-11-12 US disclosed
EP-0893995-A1 ANTICACHECTIC COMPOSITION Takeda Chemical Industries, Ltd. (JP) 1999-02-03 EP disclosed
WO-1997037656-A1 ANTICACHECTIC COMPOSITION TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-10-16 WO disclosed