Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | TACR3 | P29371 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14763225 | 0.80 | SCN9A (0.47) | ALDH1A1CYP3A4CYP2C9CYP2C19SCN9A | |
| SCHEMBL14763226 | 0.80 | SCN9A (0.47) | ALDH1A1CYP3A4CYP2C9CYP2C19SCN9A | |
| SCHEMBL3463367 | 0.79 | SMN1; SMN2 (0.43) | CYP2C9CYP2C19MAPTSMN1; SMN2 | |
| SCHEMBL28450250 | 0.74 | ATM (0.51) | ALDH1A1CA12CA1CA7CA14 | |
| SCHEMBL29253631 | 0.74 | KMT2A (0.56) | CA12CA1CA7CA14SCN9A | |
| SCHEMBL29253670 | 0.74 | KMT2A (0.56) | CA12CA1CA7CA14SCN9A | |
| SCHEMBL27496212 | 0.72 | SCN9A (0.47) | SCN9ARAB9ANPC1MAPTATM | |
| SCHEMBL395106 | 0.72 | SCN9A (0.47) | SCN9ARAB9ANPC1MAPTATM | |
| SCHEMBL395107 | 0.72 | SCN9A (0.47) | SCN9ARAB9ANPC1MAPTATM | |
| SCHEMBL28359858 | 0.70 | SCN9A (0.48) | CYP3A4CA12CA1CA7CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010435-A2 | FUSED OXAZOLE AND THIAZOLE DERIVATIVES AS TRPMS MODULATORS | GLENMARK PHARMACEUTICAL S.A. (CH) | 2010-01-28 | — | — | WO | disclosed |