Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ACP3 | P15309 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3463433 | 0.79 | ALDH1A1 (0.43) | SMN1; SMN2MAPTCYP2C9CYP2C19 | |
| SCHEMBL11497489 | 0.73 | SMN1; SMN2 (0.47) | SMN1; SMN2ACP3L3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL12671895 | 0.71 | SMN1; SMN2 (0.57) | SMN1; SMN2ACP3MAPTL3MBTL1TSHR | |
| SCHEMBL17078082 | 0.71 | SMN1; SMN2 (0.57) | SMN1; SMN2ACP3MAPTL3MBTL1TSHR | |
| SCHEMBL12671909 | 0.71 | SMN1; SMN2 (0.57) | SMN1; SMN2ACP3MAPTL3MBTL1TSHR | |
| SCHEMBL3284648 | 0.71 | SIGMAR1 (0.44) | SMN1; SMN2MAPTL3MBTL1CYP2C9TSHR | |
| SCHEMBL19985055 | 0.71 | SMN1; SMN2 (0.51) | SMN1; SMN2ACP3MAPTL3MBTL1TSHR | |
| SCHEMBL2450662 | 0.71 | SMN1; SMN2 (0.51) | SMN1; SMN2ACP3MAPTL3MBTL1TSHR | |
| Hydrochloric Acid SCHEMBL2528761 | 0.70 | SMN1; SMN2 (0.55) | SMN1; SMN2ACP3MAPTL3MBTL1TSHR | |
| SCHEMBL29156290 | 0.70 | SIGMAR1 (0.54) | SMN1; SMN2MAPTL3MBTL1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010435-A2 | FUSED OXAZOLE AND THIAZOLE DERIVATIVES AS TRPMS MODULATORS | GLENMARK PHARMACEUTICAL S.A. (CH) | 2010-01-28 | — | — | WO | disclosed |