Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29940 | 0.83 | ACHE (0.56) | TSHRZDHHC20ZDHHC2EPHX1ACHE | |
| SCHEMBL6332081 | 0.81 | EPHX1 (0.59) | TSHRZDHHC20ZDHHC2EPHX1ACHE | |
| SCHEMBL8769159 | 0.81 | EPHX1 (0.59) | TSHRZDHHC20ZDHHC2EPHX1ACHE | |
| SCHEMBL27357894 | 0.81 | EPHX1 (0.59) | TSHRZDHHC20ZDHHC2EPHX1ACHE | |
| SCHEMBL8769221 | 0.81 | EPHX1 (0.59) | TSHRZDHHC20ZDHHC2EPHX1ACHE | |
| SCHEMBL6332791 | 0.81 | EPHX1 (0.59) | TSHRZDHHC20ZDHHC2EPHX1ACHE | |
| SCHEMBL14328774 | 0.81 | EPHX1 (0.59) | TSHRZDHHC20ZDHHC2EPHX1ACHE | |
| SCHEMBL8769636 | 0.81 | EPHX1 (0.59) | TSHRZDHHC20ZDHHC2EPHX1ACHE | |
| SCHEMBL10349440 | 0.81 | EPHX1 (0.59) | TSHRZDHHC20ZDHHC2EPHX1ACHE | |
| SCHEMBL11090012 | 0.80 | EPHX1 (0.47) | EPHX1HDAC1HDAC3HDAC2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010435-A2 | FUSED OXAZOLE AND THIAZOLE DERIVATIVES AS TRPMS MODULATORS | GLENMARK PHARMACEUTICAL S.A. (CH) | 2010-01-28 | — | — | WO | disclosed |