SCHEMBL3463535

SCHEMBL3463535

CCCCCCCCCCCCCCCCC(C)(C(N)=O)c1ccc(C(C)(CCCCCCCCCCCCCCCC)C(=O)O)cc1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SCN5A Q14524 3/20 0.44
SCN9A Q15858 3/20 0.44
CNR2 P34972 7/20 0.42
CNR1 P21554 6/20 0.42
HDAC3 O15379 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC2 Q92769 1/20 0.38
NAAA Q02083 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
S1PR4 O95977 1/20 0.36
S1PR1 P21453 1/20 0.36
S1PR3 Q99500 1/20 0.36
S1PR5 Q9H228 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL517083 0.94 SCN5A (0.48) SCN5ASCN9ACNR2CNR1HDAC3
SCHEMBL26614473 0.89 SCN5A (0.51) SCN5ASCN9ACNR2CNR1NAAA
SCHEMBL26614644 0.87 MAPT (0.50) SCN5ASCN9ACNR2CNR1NAAA
SCHEMBL3242856 0.85 GAA (0.44) SCN5ASCN9ANAAA
SCHEMBL29456058 0.85 GAA (0.44) SCN5ASCN9ANAAA
SCHEMBL6344599 0.85 GAA (0.44) SCN5ASCN9ANAAA
SCHEMBL29456136 0.85 GAA (0.44) SCN5ASCN9ANAAA
SCHEMBL11290742 0.84 TP53 (0.50) HDAC3HDAC1HDAC2MAPTKMT2A
SCHEMBL5067238 0.84 CNR2 (0.40) CNR2CNR1HDAC3HDAC1HDAC2
SCHEMBL28729552 0.84 GAA (0.43) SCN5ASCN9ANAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2664454-B1 METAL-RUBBER LAMINATE MATERIAL NOK CORP (JP) 2016-04-27 EP disclosed
US-9156998-B2 Coating agent NOK CORPORATION (JP) 2015-10-13 US disclosed
EP-2664454-A1 METAL-RUBBER LAMINATE MATERIAL Nok Corporation (JP) 2013-11-20 EP disclosed
US-20130285334-A1 METAL-RUBBER LAMINATE MATERIAL NOK CORPORATION (JP) 2013-10-31 US disclosed
EP-2135903-B1 COATING AGENT NOK CORP (JP) 2012-06-20 EP disclosed
US-20100136352-A1 COATING AGENT NOK CORPORATION (JP) 2010-06-03 US disclosed
EP-2135903-A1 COATING AGENT NOK Corporation (JP) 2009-12-23 EP disclosed