SCHEMBL346364

SCHEMBL346364

CCCCCCCCCCCCCOP(=O)(S)SCCCCCCCCCCCCC.[Zn]

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 8/20 0.48
LPAR2 Q9HBW0 6/20 0.48
LPAR1 Q92633 3/20 0.48
CYP3A4 P08684 1/20 0.41
LMNA P02545 1/20 0.40
ESR1 P03372 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
CDC25A P30304 1/20 0.40
AGTR1 P30556 1/20 0.40
AKT1 P31749 1/20 0.40
ADRA1A P35348 1/20 0.40
KCNH2 Q12809 1/20 0.40
LPAR5 Q9H1C0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL163987 1.00 LPAR3 (0.48) LPAR3LPAR2LPAR1CYP3A4LMNA
SCHEMBL163339 1.00 LPAR3 (0.48) LPAR3LPAR2LPAR1CYP3A4LMNA
SCHEMBL346115 1.00 LPAR3 (0.48) LPAR3LPAR2LPAR1CYP3A4LMNA
SCHEMBL164627 1.00 LPAR3 (0.48) LPAR3LPAR2LPAR1CYP3A4LMNA
SCHEMBL164249 1.00 LPAR3 (0.48) LPAR3LPAR2LPAR1CYP3A4LMNA
SCHEMBL21044742 1.00 LPAR3 (0.48) LPAR3LPAR2LPAR1CYP3A4LMNA
SCHEMBL346738 1.00 LPAR3 (0.48) LPAR3LPAR2LPAR1CYP3A4LMNA
SCHEMBL345958 1.00 LPAR3 (0.48) LPAR3LPAR2LPAR1CYP3A4LMNA
SCHEMBL345931 1.00 LPAR3 (0.48) LPAR3LPAR2LPAR1CYP3A4LMNA
SCHEMBL164652 1.00 LPAR3 (0.48) LPAR3LPAR2LPAR1CYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4171558-A Cutting oil composition for processing cemented carbide skiving hob IDEMITSU KOSAN CO., LTD. (JP) 1979-10-23 US claimed
EP-1612258-B1 Use of additives in a lubricant composition for automotive driving system TONENGENERAL SEKIYU KK (JP) 2018-11-21 EP disclosed
US-20120012076-A1 METHOD OF OPERATING A HYBRID ENGINE CASTROL LIMITED (GB) 2012-01-19 US disclosed
WO-2010046620-A1 METHOD OF OPERATING A HYBRID ENGINE CASTROL LIMITED (GB) 2010-04-29 WO disclosed
EP-2177596-A1 Method of operating a hybrid engine Castrol Limited (GB) 2010-04-21 EP disclosed
US-7399736-B2 Low viscosity, high abrasion resistance engine oil composition TONENGENERAL SEKIYU K.K. (JP) 2008-07-15 US disclosed
EP-1612258-A2 Lubricant composition for automotive driving system TonenGeneral Sekiyu Kabushiki Kaisha (JP) 2006-01-04 EP disclosed
US-20050267002-A1 Lubricant composition for automobile driving system KATO TOMOHIRO 2005-12-01 US disclosed
EP-1600495-A1 A low viscosity, high abrasion resistance engine oil composition TonenGeneral Sekiyu Kabushiki Kaisha (JP) 2005-11-30 EP disclosed
US-20050221998-A1 Low viscosity, high abrasion resistance engine oil composition MARUMO MIYOSHI 2005-10-06 US disclosed
US-4171558-A Cutting oil composition for processing cemented carbide skiving hob IDEMITSU KOSAN CO., LTD. (JP) 1979-10-23 US disclosed