SCHEMBL346115

SCHEMBL346115

CCCCCCCCCCCCCCCCCCOP(=O)(S)SCCCCCCCCCCCCCCCCCC.[Zn]

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 8/20 0.48
LPAR2 Q9HBW0 6/20 0.48
LPAR1 Q92633 3/20 0.48
CYP3A4 P08684 1/20 0.41
LMNA P02545 1/20 0.40
ESR1 P03372 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
CDC25A P30304 1/20 0.40
AGTR1 P30556 1/20 0.40
AKT1 P31749 1/20 0.40
ADRA1A P35348 1/20 0.40
KCNH2 Q12809 1/20 0.40
LPAR5 Q9H1C0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL163987 1.00 LPAR3 (0.48) LPAR3LPAR2LPAR1CYP3A4LMNA
SCHEMBL163339 1.00 LPAR3 (0.48) LPAR3LPAR2LPAR1CYP3A4LMNA
SCHEMBL164627 1.00 LPAR3 (0.48) LPAR3LPAR2LPAR1CYP3A4LMNA
SCHEMBL164249 1.00 LPAR3 (0.48) LPAR3LPAR2LPAR1CYP3A4LMNA
SCHEMBL21044742 1.00 LPAR3 (0.48) LPAR3LPAR2LPAR1CYP3A4LMNA
SCHEMBL346738 1.00 LPAR3 (0.48) LPAR3LPAR2LPAR1CYP3A4LMNA
SCHEMBL345958 1.00 LPAR3 (0.48) LPAR3LPAR2LPAR1CYP3A4LMNA
SCHEMBL345931 1.00 LPAR3 (0.48) LPAR3LPAR2LPAR1CYP3A4LMNA
SCHEMBL346364 1.00 LPAR3 (0.48) LPAR3LPAR2LPAR1CYP3A4LMNA
SCHEMBL164652 1.00 LPAR3 (0.48) LPAR3LPAR2LPAR1CYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113388435-B Automobile back door electric stay bar lubricating grease composition and application thereof 中国石油化工股份有限公司 2023-01-17 CN disclosed
CN-113388435-A Automobile back door electric stay bar lubricating grease composition and application thereof 中国石油化工股份有限公司 2021-09-14 CN disclosed
EP-1612258-B1 Use of additives in a lubricant composition for automotive driving system TONENGENERAL SEKIYU KK (JP) 2018-11-21 EP disclosed
EP-1443061-B2 Sulfurized polyisobutylene based wear and oxidation inhibitors CHEVRON ORONITE CO (US) 2012-10-31 EP disclosed
EP-2287210-B1 Sulfurized polyisobutylene based wear and oxidation inhibitors CHEVRON ORONITE CO (US) 2012-07-18 EP disclosed
US-8138130-B2 Fused-ring aromatic amine based wear and oxidation inhibitors for lubricants CHEVRON ORONITE COMPANY LLC (US) 2012-03-20 US disclosed
US-20120012076-A1 METHOD OF OPERATING A HYBRID ENGINE CASTROL LIMITED (GB) 2012-01-19 US disclosed
EP-1707616-B1 Fused-ring aromatic amine based wear and oxidation inhibitors for lubricants CHEVRON ORONITE CO (US) 2011-06-22 EP disclosed
EP-2287210-A2 Sulfurized polyisobutylene based wear and oxidation inhibitors Chevron Oronite Company LLC (US) 2011-02-23 EP disclosed
EP-1857474-B1 Sulfurized polyisobutylene based wear and oxidation inhibitors CHEVRON ORONITE CO (US) 2010-09-22 EP disclosed
US-20050153850-A1 Sulfurized polyisobutylene based wear and oxidation inhibitors CHEVRON ORONITE COMPANY LLC 2005-07-14 US disclosed
US-6884855-B2 Molecular weight control of polymers with wear resistance and oxidation resistance of methylvinylene polymers for lubricants CHEVRON ORONITE COMPANY LLC (US) 2005-04-26 US disclosed
US-20040152817-A1 Sulfurized polyisobutylene based wear and oxidation inhibitors CHEVRON ORONITE COMPANY LLC 2004-08-05 US disclosed
EP-1443061-A1 Sulfurized polyisobutylene based wear and oxidation inhibitors Chevron Oronite Company LLC (US) 2004-08-04 EP disclosed
US-4200543-A SULFURIZED HYDROCARBON AND A CHLORINATED HYDROCARBON CHEVRON RESEARCH COMPANY (US) 1980-04-29 US disclosed
US-4163729-A LUBRICATING OIL CHEVRON RESEARCH COMPANY (US) 1979-08-07 US disclosed
US-4089790-A Synergistic combinations of hydrated potassium borate, antiwear agents, and organic sulfide antioxidants CHEVRON RESEARCH COMPANY (US) 1978-05-16 US disclosed
US-4088587-A ANTIOXIDANT AND PHOSPHORUS-CONTAINING COMPOSITION CHEVRON RESEARCH COMPANY (US) 1978-05-09 US disclosed
US-4086172-A ANTIOXIDANTS, HYDROXY AMINES CHEVRON RESEARCH COMPANY (US) 1978-04-25 US disclosed
US-3997454-A Lubricant containing potassium borate CHEVRON RESEARCH COMPANY (US) 1976-12-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050153850-A1 Sulfurized polyisobutylene based wear and oxidation inhibitors SULT1E1, ALOX15, ALOX12 LPAR3 3029/4885LPAR2 3494/4885LPAR1 1786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.