Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 8/20 | 0.45 |
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4584874 | 0.78 | DYRK1A (0.65) | DYRK1AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL22833881 | 0.78 | MAPT (0.75) | DYRK1AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL29379319 | 0.78 | MAPT (0.75) | DYRK1AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL7219825 | 0.75 | DYRK1A (0.45) | DYRK1AKMT2AMAPK1GFERNPC1 | |
| SCHEMBL9335490 | 0.74 | RAB9A (0.50) | DYRK1AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL27815164 | 0.72 | DYRK1A (0.74) | DYRK1AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL6359608 | 0.72 | DYRK1A (0.72) | DYRK1AMEN1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL2684071 | 0.72 | DYRK1A (0.68) | DYRK1AKDM4EALDH1A1MAPK1GFER | |
| SCHEMBL5572792 | 0.72 | DYRK1A (0.49) | DYRK1AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL7848214 | 0.71 | NPC1 (0.64) | DYRK1AMAPTKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010435-A2 | FUSED OXAZOLE AND THIAZOLE DERIVATIVES AS TRPMS MODULATORS | GLENMARK PHARMACEUTICAL S.A. (CH) | 2010-01-28 | — | — | WO | disclosed |