Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.30 |
| ▸ | SELE | P16581 | 1/20 | 0.30 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3464181 | 0.79 | ALDH1A1 (0.38) | ALDH1A1ICAM1SELEVCAM1 | |
| SCHEMBL31580112 | 0.76 | — | — | |
| SCHEMBL28428385 | 0.73 | NSD1 (0.42) | ALDH1A1 | |
| SCHEMBL31147208 | 0.73 | NSD1 (0.42) | ALDH1A1 | |
| SCHEMBL2749466 | 0.72 | ALDH1A1 (0.56) | ALDH1A1 | |
| SCHEMBL16835630 | 0.72 | NPSR1 (0.37) | — | |
| SCHEMBL28941209 | 0.69 | ICAM1 (0.35) | ALDH1A1ICAM1SELEVCAM1 | |
| SCHEMBL792336 | 0.68 | TYK2 (0.40) | — | |
| SCHEMBL31579826 | 0.68 | HSP90AA1 (0.32) | ALDH1A1 | |
| SCHEMBL31357824 | 0.65 | NQO2 (0.48) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010435-A2 | FUSED OXAZOLE AND THIAZOLE DERIVATIVES AS TRPMS MODULATORS | GLENMARK PHARMACEUTICAL S.A. (CH) | 2010-01-28 | — | — | WO | disclosed |