SCHEMBL3464534

SCHEMBL3464534

FC(F)(F)c1cc([B-](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)(c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc(C(F)(F)F)c1.[IH2+]

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.42
IDO1 P14902 2/20 0.38
ADRB1 P08588 1/20 0.34
TSHR P16473 3/20 0.33
ALDH1A1 P00352 2/20 0.33
RXRA P19793 2/20 0.33
RXRB P28702 2/20 0.33
RXRG P48443 2/20 0.33
MAPT P10636 1/20 0.33
RAPGEF4 Q8WZA2 1/20 0.33
ITGB3 P05106 1/20 0.33
ITGAV P06756 1/20 0.33
KIF11 P52732 1/20 0.33
XPO1 O14980 1/20 0.31
CYP3A4 P08684 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
HIF1A Q16665 1/20 0.31
TXNRD1 Q16881 1/20 0.31
TXNRD3 Q86VQ6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL41567 0.97 CES2 (0.44) CES2IDO1ADRB1TSHRALDH1A1
SCHEMBL2451170 0.94 CES2 (0.42) CES2IDO1ADRB1TSHRALDH1A1
SCHEMBL226082 0.94 CES2 (0.42) CES2IDO1ADRB1TSHRALDH1A1
Lithium Ion SCHEMBL372808 0.94 CES2 (0.42) CES2IDO1ADRB1TSHRALDH1A1
SCHEMBL8004410 0.94 CES2 (0.42) CES2IDO1ADRB1TSHRALDH1A1
SCHEMBL6866090 0.94 CES2 (0.42) CES2IDO1ADRB1TSHRALDH1A1
SCHEMBL1451136 0.94 CES2 (0.42) CES2IDO1ADRB1TSHRALDH1A1
Ammonia Solution, Strong SCHEMBL4954250 0.94 CES2 (0.42) CES2IDO1ADRB1TSHRALDH1A1
SCHEMBL5460964 0.94 CES2 (0.42) CES2IDO1ADRB1TSHRALDH1A1
Hydrochloric Acid SCHEMBL4429117 0.94 CES2 (0.42) CES2IDO1ADRB1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010066820-A1 NEGATIVE WORKING LITHOGRAPHIC PRINTING PLATE PRECURSORS COMPRISING A REACTIVE BINDER CONTAINING ALIPHATIC BI- OR POLYCYCLIC MOIETIES EASTMAN KODAK COMPANY (US) 2010-06-17 WO disclosed