SCHEMBL34650

SCHEMBL34650

[NH]C(=O)c1ncc[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8125577 0.82 NPC1 (0.46)
SCHEMBL1324 0.80 NPC1 (0.62)
SCHEMBL2004766 0.80 NPC1 (0.52)
SCHEMBL28449908 0.78 NPC1 (0.60)
SCHEMBL10952701 0.78 NPC1 (0.60)
Hydrogen Sulfide SCHEMBL28438010 0.78 NPC1 (0.60)
Bromide SCHEMBL7371333 0.78 NPC1 (0.60)
Ammonia Solution, Strong SCHEMBL16266978 0.78 NPC1 (0.60)
SCHEMBL1491811 0.78
Hydrochloric Acid SCHEMBL3543004 0.78 NPC1 (0.60)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 267 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1730152-B1 TETRAHYDROQUINOLINE DERIVATIVES AND A PROCESS FOR PREPARING THE SAME MITSUBISHI TANABE PHARMA CORP (JP) 2012-05-02 EP claimed
US-20110039828-A1 TETRAHYDROQUINOLINE DERIVATIVES AND A PROCESS FOR PREPARING THE SAME MITSUBISHI TANABE PHARMA CORPORATION (JP) 2011-02-17 US claimed
WO-2009085256-A1 ANTI-HIV COMPOUNDS PANACOS PHARMACEUTICALS, INC. (US) 2009-07-09 WO claimed
US-20070082896-A1 Tetrahydroquinoline derivatives and a process for preparing the same TANABE SEIYAKU CO., LTD. 2007-04-12 US claimed
EP-1334143-B1 POLYMERS AND POLYMERISATION PROCESSES BIOCOMPATIBLES UK LTD (GB) 2007-02-14 EP claimed
US-20070032485-A1 Tetrahydronaphthyridine derivatives and a process for preparing the same TANABE SEIYAKU CO., LTD. 2007-02-08 US claimed
US-7160953-B2 Polymeric surface coatings BIOCOMPATIBLES UK LIMITED (GB) 2007-01-09 US claimed
EP-1732924-A2 TETRAHYDRONAPHTHYRIDINE DERIVATIVES AS CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS TANABE SEIYAKU CO., LTD. (JP) 2006-12-20 EP claimed
EP-1730152-A2 TETRAHYDROQUINOLINE DERIVATIVES AND A PROCESS FOR PREPARING THE SAME TANABE SEIYAKU CO., LTD. (JP) 2006-12-13 EP claimed
EP-1180013-B1 LOCAL DRUG DELIVERY BIOCOMPATIBLES UK LTD (GB) 2006-03-08 EP claimed
US-20030190405-A1 Polymeric surface coatings BIOCOMPATIBLES LIMITED 2003-10-09 US claimed
US-6225431-B1 COATING SURFACE OF MEDICAL DEVICE WITH POLYMER FORMED BY RADICAL POLYMERIZATION OF ETHYLENICALLY UNSATURATED MONOMERS DISPERSED OR DISSOLVED IN A SOLVENT AND THE SOLVENT IS REMOVED TO LEAVE A STABLE COATING ON SURFACE BIOCOMPATIBLES LIMITED 2001-05-01 US claimed
US-6090901-A Polymeric surface coatings BIOCOMPATIBLES LIMITED (GB) 2000-07-18 US claimed
EP-0593561-B1 POLYMERIC SURFACE COATINGS BIOCOMPATIBLES LTD (GB) 2000-03-22 EP claimed
EP-0626983-B1 POLYMERIC BLENDS WITH ZWITTERIONIC GROUPS BIOCOMPATIBLES LTD (GB) 1999-04-14 EP claimed
US-5801181-A Amino alcohol substituted cyclic compounds CELL THERAPEUTICS, INC. (US) 1998-09-01 US claimed
EP-0714417-B1 POLYMER SURFACE COATINGS BIOCOMPATIBLES LTD (GB) 1998-06-10 EP claimed
US-5567692-A CONTROLLING BACTERIA INFECTIONS AMERICAN CYANAMID COMPANY (US) 1996-10-22 US claimed
US-5442059-A Antibiotics for mammalian and veterninary diseases AMERICAN CYANAMID COMPANY (US) 1995-08-15 US claimed
EP-0582829-A1 9-(substituted glycyl) amido - 6-demethyl-6-deoxytetracyclines as antibiotic agents AMERICAN CYANAMID COMPANY (US) 1994-02-16 EP claimed