SCHEMBL346563

SCHEMBL346563

CCCCCCCCOc1cc2ccccc2cc1OCCCCCCCC

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 4/20 0.64
PPARG P37231 2/20 0.53
PPARA Q07869 2/20 0.53
LTA4H P09960 1/20 0.52
TSHR P16473 1/20 0.51
MEN1 O00255 1/20 0.51
NR1I2 O75469 1/20 0.51
LMNA P02545 1/20 0.51
CHRM2 P08172 1/20 0.51
CYP3A4 P08684 1/20 0.51
ADRA2A P08913 1/20 0.51
MAPT P10636 1/20 0.51
OPRK1 P41145 1/20 0.51
HTR2B P41595 1/20 0.51
SLC6A3 Q01959 1/20 0.51
KMT2A Q03164 1/20 0.51
HDAC6 Q9UBN7 1/20 0.51
MCHR1 Q99705 2/20 0.51
CNR1 P21554 2/20 0.49
CNR2 P34972 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31290761 0.98 TLR8 (0.63) TLR8PPARGPPARALTA4HTSHR
SCHEMBL1237415 0.96 TLR8 (0.60) TLR8PPARGPPARALTA4HTSHR
SCHEMBL6473617 0.96 TLR8 (0.60) TLR8PPARGPPARALTA4HTSHR
SCHEMBL2477207 0.96 TLR8 (0.60) TLR8PPARGPPARALTA4HTSHR
SCHEMBL30844101 0.96 TLR8 (0.60) TLR8PPARGPPARALTA4HTSHR
SCHEMBL4250155 0.96 TLR8 (0.60) TLR8PPARGPPARALTA4HTSHR
SCHEMBL27768841 0.92 TLR8 (0.62) TLR8PPARGPPARALTA4HMAPT
SCHEMBL347826 0.88 TLR8 (0.58) TLR8PPARGPPARALTA4HMAPT
SCHEMBL9425423 0.88 TLR8 (0.64) TLR8PPARGPPARALTA4HTSHR
SCHEMBL11693360 0.88 TLR8 (0.56) TLR8PPARGPPARALTA4HTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120016147-A1 METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-19 US disclosed
US-8048982-B2 Method for producing aromatic compound polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-01 US disclosed
EP-2241547-A1 Method for producing aromatic compound polymer Sumitomo Chemical Company, Limited (JP) 2010-10-20 EP disclosed
EP-2241548-A1 Vanadium di-nuclear complex Sumitomo Chemical Company, Limited (JP) 2010-10-20 EP disclosed
US-20090018309-A1 Method for Producing Aromatic Compound Polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-15 US disclosed
EP-1767560-A1 METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER Sumitomo Chemical Company, Limited (JP) 2007-03-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090018309-A1 Method for Producing Aromatic Compound Polymer PAH, MAOA, AHR TLR8 2756/4885PPARG 51/4885PPARA 39/4885
US-20120016147-A1 METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER PAH, MAOA, AHR TLR8 2779/4885PPARG 54/4885PPARA 40/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.