Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 19/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3465559 | 0.95 | TRPV1 (0.47) | TRPV1 | |
| SCHEMBL3467245 | 0.83 | TRPV1 (0.47) | TRPV1 | |
| SCHEMBL3465734 | 0.82 | ESRRG (0.48) | TRPV1 | |
| SCHEMBL3465736 | 0.78 | TRPV1 (0.75) | TRPV1 | |
| SCHEMBL3465744 | 0.74 | ESRRG (0.47) | TRPV1 | |
| SCHEMBL2527167 | 0.72 | TRPV1 (0.61) | TRPV1 | |
| SCHEMBL3465556 | 0.72 | TRPV1 (0.75) | TRPV1 | |
| SCHEMBL2524768 | 0.70 | TRPV1 (0.45) | TRPV1 | |
| SCHEMBL2531659 | 0.70 | TRPV1 (0.48) | TRPV1 | |
| SCHEMBL2526774 | 0.69 | TRPV1 (0.62) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146959-A1 | VANILLOID RECEPTOR LIGANDS AND THE USE THEREOF FOR THE PRODUCTION OF PHARMACEUTICALS | Grünenthal GmbH (DE) | 2010-01-27 | — | — | EP | claimed |
| WO-2008125296-A1 | VANILLOID RECEPTOR LIGANDS AND THE USE THEREOF FOR THE PRODUCTION OF PHARMACEUTICALS | Grünenthal GmbH (DE) | 2008-10-23 | — | — | WO | claimed |
| EP-2146959-B1 | VANILLOID RECEPTOR LIGANDS AND THE USE THEREOF FOR THE PRODUCTION OF PHARMACEUTICALS | GRUENENTHAL GMBH (DE) | 2013-06-19 | — | — | EP | disclosed |
| EP-2146959-A1 | VANILLOID RECEPTOR LIGANDS AND THE USE THEREOF FOR THE PRODUCTION OF PHARMACEUTICALS | Grünenthal GmbH (DE) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008125296-A1 | VANILLOID RECEPTOR LIGANDS AND THE USE THEREOF FOR THE PRODUCTION OF PHARMACEUTICALS | Grünenthal GmbH (DE) | 2008-10-23 | — | — | WO | disclosed |