Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 4/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3465734 | 0.91 | ESRRG (0.48) | ESRRGTRPV1RAB9AKMT2A | |
| SCHEMBL4441792 | 0.78 | ESRRG (0.57) | ESRRGNPC1POLBRAB9AKMT2A | |
| SCHEMBL4431311 | 0.75 | ESRRG (0.53) | ESRRGTRPV1NPC1RAB9AKMT2A | |
| SCHEMBL4432919 | 0.75 | ESRRG (0.53) | ESRRGNPC1POLBRAB9AKMT2A | |
| SCHEMBL4435971 | 0.74 | ESRRG (0.53) | ESRRGNPC1POLBRAB9AKMT2A | |
| SCHEMBL3465737 | 0.74 | TRPV1 (0.47) | TRPV1 | |
| SCHEMBL3467245 | 0.74 | TRPV1 (0.47) | TRPV1 | |
| SCHEMBL4428485 | 0.74 | ESRRG (0.46) | ESRRGNPC1POLBRAB9AKMT2A | |
| SCHEMBL3465742 | 0.73 | TRPV1 (0.67) | TRPV1 | |
| SCHEMBL4432676 | 0.73 | ESRRG (0.50) | ESRRGNPC1POLBRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146959-A1 | VANILLOID RECEPTOR LIGANDS AND THE USE THEREOF FOR THE PRODUCTION OF PHARMACEUTICALS | Grünenthal GmbH (DE) | 2010-01-27 | — | — | EP | claimed |
| WO-2008125296-A1 | VANILLOID RECEPTOR LIGANDS AND THE USE THEREOF FOR THE PRODUCTION OF PHARMACEUTICALS | Grünenthal GmbH (DE) | 2008-10-23 | — | — | WO | claimed |
| EP-2146959-A1 | VANILLOID RECEPTOR LIGANDS AND THE USE THEREOF FOR THE PRODUCTION OF PHARMACEUTICALS | Grünenthal GmbH (DE) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008125296-A1 | VANILLOID RECEPTOR LIGANDS AND THE USE THEREOF FOR THE PRODUCTION OF PHARMACEUTICALS | Grünenthal GmbH (DE) | 2008-10-23 | — | — | WO | disclosed |