Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.47 |
| ▸ | SMO | Q99835 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3466147 | 0.92 | ALDH1A1 (0.55) | ALDH1A1HSD17B10KDM4ESMONPC1 | |
| SCHEMBL3466292 | 0.91 | ALDH1A1 (0.56) | ALDH1A1HSD17B10KDM4ESMONPC1 | |
| SCHEMBL3469326 | 0.91 | ALDH1A1 (0.49) | ALDH1A1HSD17B10KDM4ESMONPC1 | |
| SCHEMBL3466882 | 0.90 | KDM4E (0.48) | ALDH1A1HSD17B10KDM4ESMONPC1 | |
| SCHEMBL3467187 | 0.89 | KDM4E (0.48) | ALDH1A1HSD17B10KDM4ESMONPC1 | |
| SCHEMBL23008972 | 0.87 | ALDH1A1 (0.49) | ALDH1A1HSD17B10KDM4ESMONPC1 | |
| SCHEMBL3466584 | 0.86 | KDM4E (0.48) | ALDH1A1HSD17B10KDM4ESMONPC1 | |
| SCHEMBL3466582 | 0.85 | KDM4E (0.48) | ALDH1A1HSD17B10KDM4ESMONPC1 | |
| SCHEMBL3467710 | 0.84 | KDM4E (0.46) | ALDH1A1HSD17B10KDM4ESMONPC1 | |
| SCHEMBL3469191 | 0.83 | HTT (0.56) | ALDH1A1HSD17B10KDM4ESMONPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | claimed |
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | disclosed |