Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 8/20 | 0.55 |
| ▸ | BRAF | P15056 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | TTK | P33981 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12409291 | 0.85 | PIM1 (0.46) | CTSCBRAFMAPKAPK5EGFRFYN | |
| SCHEMBL8246219 | 0.85 | FYN (0.53) | CTSCCYP1A2MAPKAPK5EGFRFYN | |
| SCHEMBL14767492 | 0.84 | PIM1 (0.45) | CTSCBRAFMAPKAPK5EGFRFYN | |
| SCHEMBL3466230 | 0.81 | MAPT (0.47) | CTSCBRAFCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3466296 | 0.79 | POLB (0.48) | BRAFEGFRFYNTTK | |
| SCHEMBL3466900 | 0.78 | CTSC (0.52) | CTSCCYP1A2CYP3A4CYP2C9TTK | |
| SCHEMBL3466253 | 0.78 | MC4R (0.54) | CTSCBRAFEGFRFYNTTK | |
| SCHEMBL3466346 | 0.77 | TTK (0.45) | CTSCCYP1A2CYP3A4CYP2C9EGFR | |
| SCHEMBL3466303 | 0.77 | GAA (0.53) | BRAFCYP1A2CYP3A4CYP2C9FYN | |
| SCHEMBL3466340 | 0.77 | CLK4 (0.55) | CYP1A2CYP3A4CYP2D6CYP2C9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | claimed |
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | disclosed |