⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541522 | 0.58 | — | — | |
| SCHEMBL18697772 | 0.57 | — | — | |
| SCHEMBL17734076 | 0.57 | — | — | |
| SCHEMBL12928288 | 0.57 | CYP1A2 (0.34) | — | |
| SCHEMBL18697771 | 0.55 | — | — | |
| SCHEMBL7400825 | 0.54 | — | — | |
| SCHEMBL7262665 | 0.54 | NPC1 (0.38) | — | |
| SCHEMBL21215341 | 0.53 | — | — | |
| SCHEMBL4523631 | 0.53 | LMNA (0.33) | — | |
| SCHEMBL529582 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265600-A1 | PYRIDINYL AMIDES FOR THE TREATMENT OF CNS AND METABOLIC DISORDERS | Pfizer Inc. (US) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009098576-A1 | PYRIDINYL AMIDES FOR THE TREATMENT OF CNS AND METABOLIC DISORDERS | PFIZER INC. (US) | 2009-08-13 | — | — | WO | disclosed |