Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.55 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3468042 | 0.88 | KCNA5 (0.56) | LMNAGAAKCNA5KCNH2SLC1A2 | |
| SCHEMBL16967414 | 0.87 | KCNA5 (0.55) | LMNAGAAKCNA5KCNN4KCNH2 | |
| SCHEMBL3220273 | 0.86 | KCNA5 (0.50) | LMNAGAAKCNA5KCNN4KCNH2 | |
| SCHEMBL15797569 | 0.85 | KCNA5 (0.52) | LMNAGAAKCNA5KCNN4KCNH2 | |
| SCHEMBL2227113 | 0.81 | LMNA (0.96) | LMNAGAAKCNA5KCNH2CYP1A2 | |
| SCHEMBL628330 | 0.81 | LMNA (0.96) | LMNAGAAKCNA5KCNH2CYP1A2 | |
| Hydrochloric Acid SCHEMBL15063253 | 0.80 | LMNA (1.00) | LMNAGAAKCNA5KCNH2CYP1A2 | |
| SCHEMBL2554530 | 0.80 | GAA (0.96) | LMNAGAAKCNA5KCNH2CYP1A2 | |
| SCHEMBL628011 | 0.80 | GAA (0.96) | LMNAGAAKCNA5KCNH2CYP1A2 | |
| SCHEMBL1808956 | 0.80 | GAA (0.96) | LMNAGAAKCNA5KCNH2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069069-A1 | CATHEPSIN B INHIBITORS | MERCK FROSST CANADA LTD. (CA) | 2010-06-24 | — | — | WO | disclosed |