Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.33 |
| ▸ | PPOX | P50336 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | IDH2 | P48735 | 1/20 | 0.31 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.31 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.31 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6952332 | 0.92 | SLC6A3 (0.36) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL8484373 | 0.87 | MEN1 (0.38) | MEN1KMT2AGAAMAPTP2RX3 | |
| SCHEMBL8485274 | 0.87 | MEN1 (0.36) | MEN1KMT2AGAAMAPTP2RX3 | |
| SCHEMBL6947257 | 0.84 | SLC6A3 (0.37) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL6543753 | 0.84 | MEN1 (0.38) | MEN1KMT2AGAAMAPTP2RX3 | |
| SCHEMBL8366554 | 0.84 | MEN1 (0.36) | MEN1KMT2AP2RX3L3MBTL1ALDH1A1 | |
| SCHEMBL7768719 | 0.81 | MEN1 (0.40) | MEN1KMT2AP2RX3L3MBTL1CREBBP | |
| SCHEMBL7768729 | 0.81 | MEN1 (0.40) | MEN1KMT2AL3MBTL1CREBBP | |
| SCHEMBL6492354 | 0.80 | MEN1 (0.37) | MEN1KMT2AL3MBTL1ALDH1A1CREBBP | |
| SCHEMBL7956480 | 0.80 | MEN1 (0.39) | MEN1KMT2AGAAMAPTP2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010071575-A1 | QUATERNARY PIPERIDINE DERIVATIVES AND USES THEREOF | ASTRAZENECA AB (SE) | 2010-06-24 | — | — | WO | disclosed |