Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 20/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3461738 | 0.88 | MAPK1 (0.43) | MAPK1 | |
| SCHEMBL3461567 | 0.87 | MAPK1 (0.50) | MAPK1 | |
| SCHEMBL3462783 | 0.85 | MAPK1 (0.43) | MAPK1 | |
| SCHEMBL3462829 | 0.85 | MAPK1 (0.44) | MAPK1 | |
| SCHEMBL3460543 | 0.85 | MAPK1 (0.43) | MAPK1 | |
| SCHEMBL3462191 | 0.81 | MAPK1 (0.45) | MAPK1 | |
| Hydrochloric Acid SCHEMBL3460920 | 0.80 | MAPK1 (0.44) | MAPK1 | |
| SCHEMBL3466878 | 0.79 | MAPK1 (0.33) | MAPK1 | |
| SCHEMBL3879237 | 0.78 | CHRM3 (0.37) | MAPK1 | |
| SCHEMBL3462636 | 0.78 | NTRK1 (0.44) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7704995-B2 | Protein kinase modulators and methods of use | EXELIXIS, INC. (US) | 2010-04-27 | — | — | US | claimed |