Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.44 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | PTAFR | P25105 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12409255 | 0.85 | TTK (0.52) | TTKGAAADORA3THRBMAPT | |
| SCHEMBL3469243 | 0.84 | ADORA3 (0.51) | TTKGAAADORA3THRBMAPT | |
| SCHEMBL12409250 | 0.84 | ZAP70 (0.51) | TTKADORA3MAPTZAP70KARS1 | |
| SCHEMBL12409242 | 0.82 | TTK (0.56) | TTKADORA3MAPT | |
| SCHEMBL12409270 | 0.81 | FYN (0.58) | TTKGAAADORA3MAPTTP53 | |
| SCHEMBL13937882 | 0.81 | TTK (0.52) | TTKGAAADORA3THRBMAPT | |
| SCHEMBL12409315 | 0.81 | CYP1A2 (0.47) | TTKGAAADORA3THRBMAPT | |
| SCHEMBL12409228 | 0.80 | CA1 (0.52) | TTKGAATHRBMAPTZAP70 | |
| SCHEMBL12409317 | 0.80 | TTK (0.48) | TTKGAAADORA3THRBMAPT | |
| SCHEMBL5401140 | 0.79 | FLT3 (0.55) | TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | claimed |
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | disclosed |