Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 2/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | FYN | P06241 | 6/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12409294 | 0.88 | TTK (0.61) | TTKADORA3FLT3ADORA2AFYN | |
| SCHEMBL3469185 | 0.87 | TTK (0.68) | TTKADORA3FLT3ADORA2AFYN | |
| SCHEMBL12409279 | 0.82 | TTK (0.70) | TTKADORA3FLT3ADORA2AFYN | |
| SCHEMBL3467192 | 0.81 | TTK (0.56) | TTKADORA3FLT3ADORA2AFYN | |
| SCHEMBL12409308 | 0.81 | FYN (0.59) | TTKADORA3FLT3ADORA2AFYN | |
| SCHEMBL3466990 | 0.80 | ADORA3 (0.52) | TTKADORA3ADORA2ACLK4CYP1A2 | |
| SCHEMBL12340253 | 0.80 | TTK (0.64) | TTKADORA3FLT3FYN | |
| SCHEMBL3467195 | 0.79 | TTK (0.61) | TTKADORA3FLT3ADORA2AFYN | |
| SCHEMBL9938222 | 0.79 | ADORA3 (0.59) | TTKADORA3FLT3ADORA2AFYN | |
| SCHEMBL12409306 | 0.77 | SYK (0.49) | TTKADORA3ADORA2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | claimed |
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | disclosed |