Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 13/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | FLT3 | P36888 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12409238 | 0.88 | TTK (0.53) | TTKADORA3FLT3 | |
| SCHEMBL12409323 | 0.84 | PIK3CA (0.46) | TTKADORA3FLT3KDM4EALDH1A1 | |
| SCHEMBL9966195 | 0.83 | TTK (0.74) | TTK | |
| SCHEMBL12409319 | 0.80 | TTK (0.47) | TTK | |
| SCHEMBL12409271 | 0.80 | TTK (0.56) | TTKADORA3KDM4EALDH1A1CYP1A2 | |
| SCHEMBL3466249 | 0.79 | PTGDR (0.44) | TTKADORA3ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL12409227 | 0.78 | TTK (0.51) | TTKADORA3FLT3 | |
| SCHEMBL12409289 | 0.77 | TTK (0.56) | TTKADORA3FLT3 | |
| SCHEMBL3469482 | 0.77 | TTK (0.71) | TTKFLT3 | |
| SCHEMBL12409288 | 0.76 | TTK (0.55) | TTKADORA3KDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | claimed |
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | disclosed |