SCHEMBL3469482

SCHEMBL3469482

CC(C)CNc1nccn2c(-c3ccc(CO)cc3)cnc12

nearest known ligand 0.71

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TTK P33981 19/20 0.71
FLT3 P36888 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3467927 0.88 TTK (0.74) TTKFLT3
SCHEMBL9938190 0.84 TTK (0.82) TTK
SCHEMBL3466904 0.84 TTK (0.69) TTK
SCHEMBL9966502 0.83 TTK (0.69) TTK
SCHEMBL12409289 0.81 TTK (0.56) TTKFLT3
SCHEMBL12409288 0.81 TTK (0.55) TTK
SCHEMBL3469554 0.80 TTK (0.64) TTK
SCHEMBL12409238 0.80 TTK (0.53) TTKFLT3
SCHEMBL3466151 0.80 TTK (0.62) TTKFLT3
SCHEMBL3469505 0.80 TTK (0.57) TTKFLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010069684-A1 COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY BIOMARIN IGA, LTD. (BS) 2010-06-24 WO claimed
WO-2010069684-A1 COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY BIOMARIN IGA, LTD. (BS) 2010-06-24 WO disclosed