Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA4 | P22748 | 3/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11154756 | 0.97 | CA1 (0.48) | KMT2ACA1CA2CA4TRIM24 | |
| SCHEMBL8522333 | 0.81 | KMT2A (0.46) | KMT2ACA1CA2CA4TRIM24 | |
| SCHEMBL8776291 | 0.81 | KMT2A (0.46) | KMT2ACA1CA2CA4TRIM24 | |
| SCHEMBL10760687 | 0.81 | KMT2A (0.46) | KMT2ACA1CA2CA4TRIM24 | |
| SCHEMBL2632690 | 0.80 | — | — | |
| SCHEMBL28708985 | 0.78 | — | — | |
| SCHEMBL27709486 | 0.75 | ALDH1A1 (0.43) | KMT2ACA1CA2CA4ALDH1A1 | |
| SCHEMBL14537424 | 0.73 | CA1 (0.40) | KMT2ACA1CA2CA4MCL1 | |
| SCHEMBL6769544 | 0.70 | KMT2A (0.56) | KMT2ACA1CA2CA4TRIM24 | |
| SCHEMBL6764761 | 0.70 | KMT2A (0.56) | KMT2ACA1CA2CA4TRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018228700-A1 | FINASTERIDE FOR USE IN THE TREATMENT OF ANDROGENETIC ALOPECIA | MERZ PHARMA GMBH & CO. KGAA (DE) | 2018-12-20 | — | — | WO | disclosed |
| WO-2018206077-A1 | EMULSION COMPRISING FINASTERIDE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2018-11-15 | — | — | WO | disclosed |
| WO-2010069519-A1 | TOPICAL COMPOSITIONS COMPRISING AT LEAST ONE ACTIVE INGREDIENT POORLY SOLUBLE IN WATER AND BIOPOLYMERS SUCH AS HYALURONIC ACID WITH A PKA-VALUE BETWEEN 5-7 | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-24 | — | — | WO | disclosed |