Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924479 | 0.89 | CNR2 (0.51) | CNR2CNR1MAPTHDAC1HDAC6 | |
| SCHEMBL3467494 | 0.88 | HDAC1 (0.55) | CNR2CNR1MAPTHDAC1HDAC6 | |
| SCHEMBL3467482 | 0.80 | MAPT (0.52) | CNR2MAPTHDAC1HDAC6MEN1 | |
| SCHEMBL3467572 | 0.79 | HDAC1 (0.51) | CNR2CNR1MAPTHDAC1HDAC6 | |
| SCHEMBL7926022 | 0.79 | HPGD (0.53) | CNR2CNR1HDAC1HDAC6HDAC3 | |
| SCHEMBL3467882 | 0.78 | HDAC1 (0.50) | MAPTHDAC1HDAC6HDAC3HTT | |
| SCHEMBL3468955 | 0.78 | NPC1 (0.51) | MAPTHDAC1HDAC6MEN1KMT2A | |
| SCHEMBL3467928 | 0.78 | HDAC1 (0.60) | CNR2CNR1HDAC1HDAC6HDAC3 | |
| SCHEMBL3467762 | 0.77 | HDAC1 (0.62) | CNR2CNR1HDAC1HDAC6MEN1 | |
| SCHEMBL3467299 | 0.77 | HDAC1 (0.53) | CNR2CNR1MAPTHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |
| WO-2010073078-A2 | HETEROCYCLIC COMPOUNDS AS HDAC INHIBITORS | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2010-07-01 | — | — | WO | disclosed |
| WO-2010073078-A2 | HETEROCYCLIC COMPOUNDS AS HDAC INHIBITORS | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2010-07-01 | — | — | WO | disclosed |