Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PYGL | P06737 | 2/20 | 0.41 |
| ▸ | PYGM | P11217 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3710805 | 0.86 | HSD17B10 (0.49) | EGFRMAPTGAAALDH1A1CYP1A2 | |
| SCHEMBL10789976 | 0.82 | IDO1 (0.46) | GAAALDH1A1BRD4CREBBPGLA | |
| SCHEMBL16399613 | 0.81 | CREBBP (0.47) | MAPTGAABRD4CREBBPAHR | |
| SCHEMBL16399610 | 0.79 | CREBBP (0.49) | MAPTGAAALDH1A1BRD4CREBBP | |
| SCHEMBL5140200 | 0.79 | ALDH1A1 (0.45) | MAPTGAAALDH1A1BRD4CREBBP | |
| SCHEMBL30563086 | 0.79 | ALDH1A1 (0.45) | MAPTGAAALDH1A1BRD4CREBBP | |
| SCHEMBL2092913 | 0.78 | CREBBP (0.51) | MAPTGAABRD4CREBBPAHR | |
| SCHEMBL28119208 | 0.78 | CREBBP (0.47) | MAPTGAAALDH1A1BRD4CREBBP | |
| SCHEMBL7423254 | 0.78 | CREBBP (0.51) | MAPTGAABRD4CREBBPAHR | |
| SCHEMBL30169994 | 0.77 | IDO1 (0.58) | MAPTGAABRD4CREBBPPYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074807-A1 | 3, 4-DIHYDROQUINOLIN-2 ( 1H ) -ONE DERIVATIVES AS SODIUM CHANNEL MODULATORS | GILEAD PALO ALTO, INC. (US) | 2010-07-01 | — | — | WO | disclosed |
| US-4677112-A | 1,2,3,4-tetrahydro-2-oxo-8-quinolineacetic and -propanoic acids and derivatives as cognition activators | WARNER-LAMBERT COMPANY (US) | 1987-06-30 | — | — | US | disclosed |